YiqiJiangzhuoHuoxueTongluo Method to Delay the Occurrence of End-stage Renal Disease in Diabetic Kidney Disease--Study2

Prior treatment

• 1 Patients who are currently receiving other traditional Chinese medicines and Chinese patent medicines with DKD therapeutic effects ;
• 4 Patients who participated in any other research drug study and / or received or had received another research drug or intervention treatment ( within one month before signing the informed consent form ) ;
• 11 patients with maintenance dialysis \> 2 weeks and / or expected maintenance dialysis \> 8 weeks before treatment and patients who were judged by any researcher not suitable for inclusion in the trial.

Other illness

• 2 combined with other clear renal diseases, such as polycystic kidney disease, glomerulonephritis, renal tumors ;
• 3 Patients with acute or chronic infection who needed treatment were judged by the researchers not suitable for inclusion in the study ;
• 5 patients who were allergic or contraindicated to the planned use of drugs ;
• 6 There are serious acute or chronic diseases that the major researchers believe may pose an excessive risk to the subjects, including : patients with cardiovascular, cerebrovascular, lung, blood, digestive tract, liver, kidney, neuropsychiatric or infectious diseases ;
• 7 Patients with a history of immunodeficiency, including patients with other acquired, congenital immunodeficiency diseases, or patients with a history of organ transplantation or planned organ transplantation ;
• 9 patients with a history of malignant tumors within 5 years ;
• 10 patients with type 1 diabetes ;

Other

• 8 Women with positive pregnancy screening test or lactating or planning to get pregnant in the next 24 months. Female or male patients who were reluctant to use contraception throughout the study period ;

• 1 In line with the diagnostic criteria of Western medicine type 2 DKD ;
• 2 18-80 years old, regardless of gender ;
• 3 30ml / min / 1.73m2 ≤ eGFR \< 60ml / min / 1.73m2 ( eGFR was calculated according to CKD-EPI formula ) ;
• 4 In line with the diagnostic criteria of qi deficiency and collateral stasis syndrome in traditional Chinese medicine ;
• 5 hbA1c between 7-10 % ;
• 6 uACR ≥ 300mg / g
• 7 blood pressure ≤ 150 / 90mmHg ;
• 8 signed the informed consent ;