NCT07034898Enrolling by invitationPhase 4
Dexmedetomidine vs Labetalol for Airway Stress in Hypertensive Craniotomy Patients
A Randomized Comparative Study of Dexmedetomidine Versus Labetalol in Attenuating Airway Stress Response in Hypertensive Patients Undergoing Craniotomy
Source: ClinicalTrials.gov · Last updated 24 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This randomized trial compares dexmedetomidine and labetalol in controlling airway and hemodynamic stress during extubation in hypertensive patients undergoing craniotomy. Outcomes include extubation quality, vital signs, sedation, and adverse effects.
- Status (registry)
- Enrolling by invitation
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 15 Jun 2025
- Start date
- 1 Apr 2025
- Primary completion date
- 31 Aug 2025
- Lead sponsor
- Ain Shams University
- Diseases
- High blood pressure
- NCT number
- NCT07034898
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 60
- From 1 Apr 2025 to the primary completion date, 31 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- ASA physical status III or IV
- Uncontrolled comorbidities (e.g., diabetes mellitus)
- Coagulopathy or current use of anticoagulant or antiplatelet therapy
- Known allergy or hypersensitivity to dexmedetomidine or labetalol
- Emergency craniotomy
- Pregnant or breastfeeding women
- Patients with a history of severe cardiac arrhythmias
- Inability to provide informed consent
Who the study is looking for
- Age between 30 and 60 years
- American Society of Anesthesiologists (ASA) physical status II
- Diagnosed hypertension
- Scheduled for elective craniotomy under general anesthesia
- Able and willing to provide informed consent
Age in the registry: 30 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ain Shams University Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.