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NCT07035470Completed

Biological Age Predicts 90-Day Mortality in Advanced Cancer

Biological Age as a Prognostic Marker in Hospitalized Patients With Advanced Cancer: A Retrospective Analysis Based on PhenoAge Model

Source: ClinicalTrials.gov · Last updated 29 Jun 2025

Brief summary (registry, in English)

This retrospective study evaluates whether biological age, calculated using the PhenoAge model, predicts short-term outcomes in patients with advanced cancer who were hospitalized. The main goal is to investigate associations between biological age and short-term mortality, functional status (ECOG), comorbidity burden (mCCI), and length of hospital stay. All data were collected from medical records without any patient intervention.

Status (registry)
Completed
Study type
Observational
Enrollment
1615 (actual)
First submitted
16 Jun 2025
Start date
5 Nov 2022
Primary completion date
31 Dec 2024
Lead sponsor
Ankara Etlik City Hospital
NCT number
NCT07035470

What you commit to

  • Study type: Observational
  • Participants enrolled: 1615
  • From 5 Nov 2022 to the primary completion date, 31 Dec 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Lab values

  • Elective hospitalizations (e.g., planned chemotherapy, biopsy)
    • Patients who died during the first admission
    • Missing required laboratory parameters
    • ICU patients and unconscious patients

Who the study is looking for

  • Hospitalized in the Medical Oncology Department between November 5, 2022, and December 31, 2024
    • Histologically confirmed advanced-stage (stage III-IV) solid tumors
    • Age ≥18 years
    • Hospital stay of at least 48 hours
    • Actively receiving chemotherapy or received it within the last 6 months
    • Availability of all 9 required laboratory tests (albumin, creatinine, glucose, CRP, lymphocyte %, MCV, RDW, ALP, WBC) for PhenoAge calculation during the first admission
    • Patients with multiple hospitalizations who meet the inclusion criteria will be included

Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Etlik City Hospital
Coordinator of this site? Confirm its status
AnkaraTurkey (Türkiye)Unknown status

This page is information, not medical advice. Discuss any trial with your doctor.