NCT07035470Completed
Biological Age Predicts 90-Day Mortality in Advanced Cancer
Biological Age as a Prognostic Marker in Hospitalized Patients With Advanced Cancer: A Retrospective Analysis Based on PhenoAge Model
Source: ClinicalTrials.gov · Last updated 29 Jun 2025
Brief summary (registry, in English)
This retrospective study evaluates whether biological age, calculated using the PhenoAge model, predicts short-term outcomes in patients with advanced cancer who were hospitalized. The main goal is to investigate associations between biological age and short-term mortality, functional status (ECOG), comorbidity burden (mCCI), and length of hospital stay. All data were collected from medical records without any patient intervention.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1615 (actual)
- First submitted
- 16 Jun 2025
- Start date
- 5 Nov 2022
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- Ankara Etlik City Hospital
- Diseases
- Childhood cancers
- NCT number
- NCT07035470
What you commit to
- Study type: Observational
- Participants enrolled: 1615
- From 5 Nov 2022 to the primary completion date, 31 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- Elective hospitalizations (e.g., planned chemotherapy, biopsy)
- Patients who died during the first admission
- Missing required laboratory parameters
- ICU patients and unconscious patients
Who the study is looking for
- Hospitalized in the Medical Oncology Department between November 5, 2022, and December 31, 2024
- Histologically confirmed advanced-stage (stage III-IV) solid tumors
- Age ≥18 years
- Hospital stay of at least 48 hours
- Actively receiving chemotherapy or received it within the last 6 months
- Availability of all 9 required laboratory tests (albumin, creatinine, glucose, CRP, lymphocyte %, MCV, RDW, ALP, WBC) for PhenoAge calculation during the first admission
- Patients with multiple hospitalizations who meet the inclusion criteria will be included
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Etlik City Hospital Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.