NCT07036211Not yet recruiting
Transmission of Oncogenic HPV Infection Among Families
Source: ClinicalTrials.gov · Last updated 25 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of the Transmission of Oncogenic HPV Infection Among Families (TREVINO) study is to improve understanding of how high-risk human papillomavirus (HPV) infections are transmitted within families. The research focuses on transmission between sexual partners and between parents and children. It also examines how the various microbes may influence the persistence of HPV infections and the development of HPV-related cancers. The study will include up to 300 couples recruited from gynecology and ear, nose, and throat (ENT) clinics in Finland, as well as their children. Participants include individuals with persistent HPV infection, cervical precancer or cancer, or HPV-related head and neck cancer, along with their partners and potentially their offspring. Participants will provide self-collected samples from the oral and genital areas at multiple time points over up to five years. Questionnaires addressing medical, behavioural, and environmental factors will be completed. The study is conducted at Tampere University Hospital and Kuopio University Hospital in Finland. Results will inform HPV screening and prevention programs, improve understanding of family-level transmission, and identify potential microbial and genetic markers linked to cancer risk.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 700 (estimated)
- First submitted
- 23 Apr 2025
- Start date
- 1 Aug 2025
- Primary completion date
- 31 May 2027
- Lead sponsor
- Tampere University Hospital
- NCT number
- NCT07036211
What you commit to
- Study type: Observational
- Planned participants: 700
- From 1 Aug 2025 to the primary completion date, 31 May 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Candidate who don't speak Finnish
Who the study is looking for
- Patient with colposcopy clinic detected persisting HR-HPV infection
- Patient with diagnosed cervical cancer
- Patient with diagnosed OSCC
- Patients' sexual partners of women or men that are referred to the colposcopy/gynecological oncology/ENT
- offspring (over 12 years old) of the referred couples
Age in the registry: 12 years to 100 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kuopio University Hospital Coordinator of this site? Confirm its status | Kuopio | Finland | Unknown status |
| Tampere University Hospital Coordinator of this site? Confirm its status | Tampere | Finland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.