NCT07037589Recruiting
Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?
Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed? A Prospective Multicenter Study. BLUSH Trial
Source: ClinicalTrials.gov · Last updated 21 Nov 2025
Brief summary (registry, in English)
This prospective multicenter observational study evaluates whether women ≥50 years with isolated acute hemorrhagic cystitis (AHC) and macroscopic hematuria require full malignancy workup. All participants undergo standard diagnostics (cystoscopy, CT urography, cytology), with 12-month follow-up for cancer detection. The aim is to identify low-risk patients where invasive investigations may be safely avoided.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 16 Jun 2025
- Start date
- 13 Oct 2025
- Primary completion date
- 30 Aug 2026
- Lead sponsor
- Vastra Gotaland Region
- Diseases
- Kidney cancer, Bladder cancer
- NCT number
- NCT07037589
What you commit to
- Study type: Observational
- Planned participants: 300
- From 13 Oct 2025 to the primary completion date, 30 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior diagnosis of bladder cancer, renal cancer, or upper tract urothelial carcinoma (UTUC).
Other illness
- Cognitive impairment preventing informed consent.
- Ongoing or recent treatment for urological malignancy.
Other
- Serious comorbidities affecting participation or safety.
- Pregnant women.
Who the study is looking for
- Women ≥50 years of age.
- Macroscopic hematuria.
- Presenting for evaluation within the SCP for macroscopic hematuria.
- Ability to provide informed consent.
Age in the registry: 18 years to 110 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Uddevalla Hospital Coordinator of this site? Confirm its status | Uddevalla | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.