NCT07039006Completed
Error Augmentation for Upper Limb Rehabilitation in Stroke Survivors
Error Augmentation for Upper Limb Rehabilitation in Stroke Survivors: a Proof-of-concept Study
Source: ClinicalTrials.gov · Last updated 26 Jun 2025
Brief summary (registry, in English)
Stroke can severely limit a person's ability to move their arm, especially when trying to reach by extending the elbow. These challenges often persist long after the stroke and make everyday activities more difficult. The investigators are testing a feedback strategy called error augmentation (EA) feedback that intentionally exaggerates movement errors to promote motor learning. In this study, the investigators designed a virtual reality training program that uses EA feedback to encourage people with chronic stroke to use more elbow extension during reaching. The EA feedback makes it appear as though the elbow is more bent than it actually is, prompting the participant to extend their elbow further than they normally would. By having the patient practice movement with enhanced feedback, the investigators predict that the patient will increase the range of motion and improve reaching ability. This is a short, proof-of-concept study to evaluate whether EA feedback shows early promise for improving arm movement in people with upper limb motor impairment after stroke. Participants are randomly assigned to either an EA training group or a control group (no-EA feedback). Each person completes three 30-minute virtual reality training sessions over 1 week. The investigators assess arm movement and motor impairment before and after training, and again one hour after the training to determine if improvements are retained. Findings from this preliminary study will help determine whether this EA-based training approach should be used in a longer 9-week clinical trial aimed at promoting long-term recovery of arm function after stroke.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 28 (actual)
- First submitted
- 9 Jun 2025
- Start date
- 1 Jan 2022
- Primary completion date
- 29 May 2025
- Lead sponsor
- McGill University
- Diseases
- Stroke
- NCT number
- NCT07039006
What you commit to
- Study type: Interventional
- Participants enrolled: 28
- From 1 Jan 2022 to the primary completion date, 29 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Has other major neurological or musculoskeletal problems that would interfere with task performance
- Has marked elbow proprioceptive deficits (\<6/12 Fugl-Meyer Assessment for the Upper-Limb (FMA-UL) Sensation Scale)
- Has visuospatial neglect (Line Bisection Test)
- Has uncorrected vision
- Has depression (\>14 on Beck Depression Inventory II)
Who the study is looking for
- Sustained a first-ever cortical/sub-cortical ischemic/hemorrhagic stroke ≥6 mo and ≤5 yr previously
- Has no medical complications
- Has arm paresis but can voluntarily flex/extend the elbow \~30 degrees
- Can provide informed consent
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jewish Rehabilitation Hospital Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.