NCT07041892Active, not recruiting
The Effects of an Oral Prebiotic and an Oral Synbiotic Supplement in Combination With a Topical Lotion and Soap On Eczema
Clinical and Instrumental Efficacy Evaluation Of Oral Prebiotic + Synbiotic Food Supplement Tested With Topical Lotion + Soap On Subjects With Atopic Dermatitis- Use Test Under Dermatological Control
Source: ClinicalTrials.gov · Last updated 27 Jun 2025
Brief summary (registry, in English)
The purpose of this study is to examine the effects of 2 dietary supplements (an oral prebiotic and an oral synbiotic) in combination with a topical lotion, and an unscented soap on eczema severity, various skin measures (such as skin hydration), and mood in those with eczema. A prebiotic supplement contains ingredients that can get broken down by the bacteria in the gut. A synbiotic supplement contains prebiotic and probiotic ingredients.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 34 (actual)
- First submitted
- 19 Jun 2025
- Start date
- 4 Apr 2025
- Primary completion date
- 6 Jun 2025
- Lead sponsor
- Codex Labs Corporation
- Diseases
- Atopic dermatitis (eczema)
- NCT number
- NCT07041892
What you commit to
- Study type: Interventional
- Participants enrolled: 34
- From 4 Apr 2025 to the primary completion date, 6 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of topical or systemic treatment during the previous weeks liable to interfere with the assessment of the cutaneous acceptability/efficacy of the study product (the subjects are allowed to use their topical corticosteroids during the study if needed; the information about the treatment and the number of applications must be noted in the daily log);
- Subject having undergone a surgery under general anesthesia within the previous month;
- Excessive exposure to sunlight or UV-rays within the previous month;
Other
- For women with childbearing potential: pregnant or nursing woman or woman planning to get pregnant during the study;
- Cutaneous pathology on the study zone (other than eczema);
- Subject enrolled in another clinical trial during the study period (concerns the studied zones).
Who the study is looking for
- Sex: female and male;
- Age : 18 years old and above;
- Phototype: I to IV;
- Type: Caucasian;
- Subjects with active eczema condition the body (showing flakiness, irritation, itch and intense dryness);
- Subjects with a SCORAD of 25 - 50;
- Local EASI score of 0-15:
- 30% - 4-5
- 30%- 6-7
- 30% - 8-9
- Subjects with dry and very dry skin on the study areas (cutaneous hydration rate \< 50 A.U);
- Subjects must not take antibiotics and / or apply any antifungal treatments (body/scalp) for 1 month before study start and during the entire study duration;
- No change in hygiene, cosmetics, and make-up habits - except for the product(s) under study - during the entire study duration;
- Subjects agreeing not to change lifestyle habits during the study duration
- Healthy subject;
- Subject having given her free informed, written consent;
- Subject willing to adhere to the protocol and study procedures;
- Subject with Polish citizenship.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Eurofins Dermscan Poland Coordinator of this site? Confirm its status | Gdansk | Poland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.