NCT07042087Recruiting
Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness
Source: ClinicalTrials.gov · Last updated 27 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The study aims to evaluate the effects of a 9-month intervention combining yoga-based mindfulness techniques, cognitive training, and nutritional counseling on cognitive function, plasma markers of neurodegeneration (tau protein), physical fitness, and metabolism in older adults at increased risk of developing Alzheimer's disease.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 48 (estimated)
- First submitted
- 11 Jun 2025
- Start date
- 1 Nov 2024
- Primary completion date
- Dec 2026
- Lead sponsor
- St. Anne's University Hospital Brno, Czech Republic
- Diseases
- Alzheimer disease
- NCT number
- NCT07042087
What you commit to
- Study type: Interventional
- Planned participants: 48
- From 1 Nov 2024 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concurrent participation in another clinical study
- Unstable iAChE medication regimen
Other illness
- Stroke or myocardial infarction within the past year
- Decompensated internal conditions (e.g., severe heart failure, kidney failure, unstable diabetes, GLP1 agonist therapy)
- Long-term psychiatric treatment (except well-managed depression)
- Neurological conditions affecting mobility or cognition (e.g., Parkinson's disease, severe tremor, epilepsy)
- Severe sensory or motor impairment preventing protocol participation
- Active cancer treated within the past 5 years
Other
- Poor anticipated compliance (e.g., transport issues, time constraints, non-cooperation)
- Substance or alcohol dependence
Who the study is looking for
- Age 60-80 years
- Diagnosis of Subjective Cognitive Impairment (SCI) or Mild Cognitive Impairment (MCI)
- mini-mental-scale (MMSE) score between 24-30
- Positive plasma pTau217 biomarker
- Stable dose of iAChE therapy (if applicable)
- Ability to participate in a 9-month intervention
Age in the registry: 60 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fnusa/ Icrc Coordinator of this site? Confirm its status | Brno | Czechia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.