NCT07043777Completed
Three-Vessel Versus Unilateral Antegrade Cerebral Perfusion in Emergency Total Arch Replacement for Acute Type A Aortic Dissection
A Retrospective Chart-Review Evaluating Direct Three-Vessel Antegrade Cerebral Perfusion Versus Unilateral Right Axillary Antegrade Cerebral Perfusion in Emergency Total Arch Replacement for Acute Type A Aortic Dissection at CMUH (2021-2025)
Source: ClinicalTrials.gov · Last updated 1 Jul 2026
Brief summary (registry, in English)
This single-centre retrospective observational cohort study describes the technical feasibility of direct three-vessel antegrade cerebral perfusion, designated modified antegrade cerebral perfusion (MACP), during emergency total arch replacement for acute type A aortic dissection. MACP delivers antegrade cerebral perfusion directly to the brachiocephalic, left common carotid, and left subclavian arteries. Outcomes are summarised descriptively and compared exploratorily with unilateral right axillary antegrade cerebral perfusion (uACP). Because perfusion strategy and treating surgeon were completely confounded, the comparative analyses are intended only to contextualise the technical experience and generate hypotheses.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 201 (actual)
- First submitted
- 20 Jun 2025
- Start date
- 1 Jan 2021
- Primary completion date
- 30 Apr 2025
- Lead sponsor
- China Medical University Hospital
- Diseases
- Stroke
- NCT number
- NCT07043777
What you commit to
- Study type: Observational
- Participants enrolled: 201
- From 1 Jan 2021 to the primary completion date, 30 Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Ischemic stroke within 30 days before surgery.
- Remote prior stroke history or unavailable prior-stroke status.
Other
- Incomplete key clinical, operative, or outcome data precluding analysis.
- Preoperative modified Rankin Scale score of 4 or higher.
- Patients managed with cerebral perfusion strategies other than MACP or uACP.
Who the study is looking for
- Adults aged 18 years or older.
- Patients who underwent emergency total arch replacement for acute type A aortic dissection at China Medical University Hospital between 1 January 2021 and 30 April 2025.
- Patients who received either direct three-vessel antegrade cerebral perfusion (MACP) or unilateral right axillary antegrade cerebral perfusion (uACP).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| China Medical University Hospital Coordinator of this site? Confirm its status | Taichung | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.