NCT07044830Recruiting
Obstructive Sleep Apnea Treatment From Acute to Chronic Phase of Stroke
Obstructive Sleep Apnea Treatment From Acute to Chronic Phase of Stroke - A Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 1 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The study aims to evaluate whether early treatment of obstructive sleep apnea with continuous positive airway pressure in ischemic stroke patients has a favorable effect on functional recovery.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 425 (estimated)
- First submitted
- 1 Jun 2025
- Start date
- 28 Feb 2024
- Primary completion date
- 28 Feb 2029
- Lead sponsor
- Hospital das Clínicas de Ribeirão Preto
- Diseases
- Stroke
- NCT number
- NCT07044830
What you commit to
- Study type: Interventional
- Planned participants: 425
- From 28 Feb 2024 to the primary completion date, 28 Feb 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior stroke
- Previous diagnosis of OSA with current CPAP use or previously failed CPAP
- Oxygen therapy \>2 L/min
- Chronic alcohol or drug use with high risk of withdrawal during hospitalization
Other illness
- Pre-stroke disability (mRS \> 1)
- Clinical instability or severe pre-existing illness (e.g., heart failure, oxygen-dependent COPD, renal or hepatic failure)
- Known severe neurological disease (e.g., dementia, Parkinson's disease, multiple sclerosis, or other neurodegenerative conditions)
Other
- Coma or stupor
- Orotracheal intubation
- Psychomotor agitation
- High likelihood of neurosurgical intervention within the first 48 hours
- Pregnant or suspected pregnant women
- Inability to complete follow-up for any reason
- Any contraindication to CPAP use
Who the study is looking for
- Supratentorial non-lacunar ischemic stroke, including anterior, middle, and posterior cerebral artery territories
- Aged 18 to 80 years
- Symptom onset or symptom recognition to admission \< 12 hours
- NIHSS score ≥ 4 and ≤ 20 at enrollment
- Signed informed consent form obtained from the participant or their legal representative
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital das Clínicas, Ribeirão Preto Medical School, University of São Paulo Coordinator of this site? Confirm its status | Ribeirão Preto | Brazil | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.