NCT07046442Completed
Effect of Pulmonary Rehabilitation and Physical Activity on COVID-19 Long-Term Symptoms (PuReCOVID)
Effect of Pulmonary Rehabilitation and Physical Activity on the Symptoms of Long COVID. A Pilot Study
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
This single-center, observational, longitudinal, retrospective and prospective study investigates the impact of Active Cycle of Breathing Technique (ACBT) and moderate daily physical activity on symptoms associated with long COVID, such as cough, dyspnea, and fatigue. The study aims to assess whether these interventions can moderately alleviate or resolve these symptoms and evaluate their potential association with small airway dysfunction (SAD), as measured by Impulse Oscillometry (IOS). The investigators will recruit 40 adult patients with long COVID who meet specific inclusion criteria. Participants will perform ACBT twice daily and complete at least 6000 steps per day for six weeks. The investigators will track clinical and lung function parameters, including spirometry, IOS, and exercise capacity.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 40 (actual)
- First submitted
- 27 Jun 2025
- Start date
- 5 Apr 2022
- Primary completion date
- 4 Feb 2025
- Lead sponsor
- University of Parma
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT07046442
What you commit to
- Study type: Observational
- Participants enrolled: 40
- From 5 Apr 2022 to the primary completion date, 4 Feb 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with other coexisting chronic lung diseases (asthma, fibrosis, bronchiectasis, sarcoidosis, interstitial diseases, pulmonary hypertension)
Other
- Active smoking patients
Who the study is looking for
- Male or female adults aged ≥18 years;
- Signed informed consent;
- Patients with long COVID
- Patients with or without ventilatory deficit (FEV1/FVC\>/≤70% and FVC\>/≤80%)
- Patients reporting at least one of the following symptoms: cough, dyspnea, and fatigue at 24 weeks post-infection
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Parma Coordinator of this site? Confirm its status | Parma | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.