NCT07050823Recruiting
Mitigating Chronic Respiratory Disease Through the Lens of Multi-Morbidity
Case-Finding for Chronic Respiratory Diseases in People Living With Other Long-Term Conditions
Source: ClinicalTrials.gov · Last updated 25 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The investigators aim to make it easier to find people with undiagnosed long-term lung health problems (such as asthma, and chronic obstructive pulmonary disease, COPD, collectively called 'Chronic Respiratory Diseases', CRDs) living in Brasil. Because people with undiagnosed CRDs often have other medical problems too, such as heart problems, high blood pressure and diabetes (collectively called 'Long Term Conditions', LTC), the investigators will look for undiagnosed CRD in people with LTC when they are attending appointments at local health centres in the cities of Sao Carlos and Sao Paulo. To look for undiagnosed CRDs the investigators will use two questionnaire-based methods called 'COLA' and 'SBQ'. These are quick and simple to do. All participants will also have tests of their lung function completed including spirometry and Fractional Exhaled Nitric Oxide so that the investigators can make a definite diagnosis of CRDs. When the study is complete, the investigators will examine how well the COLA and SBQ questionnaires perform in identifying people with a definite diagnosis of CRD. In total, the investigators aim to recruit 859 people.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 859 (estimated)
- First submitted
- 13 Jun 2025
- Start date
- 1 Jul 2025
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- University College, London
- NCT number
- NCT07050823
What you commit to
- Study type: Observational
- Planned participants: 859
- From 1 Jul 2025 to the primary completion date, 31 Dec 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Active pulmonary tuberculosis or undergoing treatment for pulmonary tuberculosis.
- Current acute respiratory infection.
- Cognitive impairment that prevents understanding of the case-finding questionnaire, defined as MMSE score ≤20.
Other
- Clinically unstable in the past month (defined as worsening symptoms requiring emergency care or hospitalization).
- Current pregnancy.
- Contraindications to spirometry.
- Declines to participate in the study.
Who the study is looking for
- Attending primary health care services in Brasil.
- Diagnosed with one or more existing, non-respiratory long-term conditions such as cardiovascular disease, diabetes or hypertension.
Age in the registry: 30 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Multiple primary care sites Coordinator of this site? Confirm its status | São Carlos | Brazil | Recruiting |
| Multiple primary care sites Coordinator of this site? Confirm its status | São Paulo | Brazil | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.