NCT07051954Recruiting
Effectiveness of Functional Respiratory Muscle Training in Post-COVID-19 Syndrome
Investigation of the Effects of Functional Respiratory Muscle Training on Respiratory Muscle Function, Exercise Capacity, Skeletal Muscle Strength, and Muscle Endurance in Individuals With Post-COVID-19 Syndrome
Source: ClinicalTrials.gov · Last updated 14 Jan 2026
Brief summary (registry, in English)
This study aims to investigate the effects of core stabilization exercises and functional inspiratory muscle training (IMT) on various physiological and psychological parameters in individuals with post-COVID-19 syndrome. Participants diagnosed with post-COVID-19 syndrome will be randomly assigned to two groups using stratified computer-assisted randomization. One group will undergo an 8-week core stabilization training, while the other will receive combined core stabilization and IMT training. Exercise training will be conducted three times a week, with each session lasting 50 minutes. Comprehensive pre- and post-intervention assessments will be conducted, including exercise capacity, respiratory and peripheral muscle strength, trunk endurance, balance, anxiety, depression, and fatigue levels. The primary outcome measures are respiratory muscle strength and trunk endurance. Participants must be aged 18-65 years, have at least a primary education level, speak Turkish, and be classified as level 2-3 on the Post-COVID-19 Functional Status Scale (PCFS). Eligible participants will be referred by the Internal Medicine Department at Hacettepe University. The study will utilize various assessment tools, including maximal inspiratory/expiratory pressure (MIP/MEP) tests, Functional Movement Screen (FMS), plank and Sorenson endurance tests, the Timed Up and Go Test for balance, handgrip and knee extension strength tests, body composition analysis, and the SF-36 quality of life questionnaire.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 3 Jul 2025
- Start date
- 15 Sept 2025
- Primary completion date
- 1 Dec 2026
- Lead sponsor
- Hacettepe University
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT07051954
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 15 Sept 2025 to the primary completion date, 1 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of recent myocardial infarction or pulmonary embolism.
- Presence of uncontrolled chronic diseases.
- Any orthopedic or neurological disorders that limit mobility.
- Neurological impairments (e.g., cerebrovascular disease) or psychiatric disorders that impair cooperation or compliance with exercise testing.
Who the study is looking for
- Diagnosed with Post-COVID-19 Syndrome.
- Literate and able to understand study procedures.
- Aged between 18 and 65 years.
- Willing to voluntarily participate in the study.
- Classified as functional class 2-3 according to the Post-COVID-19 Functional Status Scale (PCFS).
- Clinically stable; comorbid conditions such as hypertension or diabetes must be controlled.
- No orthopedic or neurological conditions that would prevent assessment of peripheral muscle strength, balance, or exercise capacity.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hacettepe University Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.