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NCT07052916Recruiting

A Music Therapy Study for Blood Cancer Survivors With Cognitive Difficulties

Pilot Trial of Telehealth Music Therapy for Cognitive Dysfunction in Hematologic Cancer Survivors (PRELUDE)

Source: ClinicalTrials.gov · Last updated 26 May 2026

Brief summary (registry, in English)

Research has shown that music-based activities may help improve brain functions, such as attention, memory, and executive function. Because of this past research, the researchers are doing this study to find out whether telehealth music therapy is a practical treatment for cognitive difficulties in blood cancer survivors. The researchers will also study whether music therapy and music education help improve cognitive function and other common symptoms such as anxiety, depression, and/or tiredness.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
60 (estimated)
First submitted
30 Jun 2025
Start date
27 Jun 2025
Primary completion date
27 Dec 2026
Lead sponsor
Memorial Sloan Kettering Cancer Center
NCT number
NCT07052916

What you commit to

  • Study type: Interventional
  • Planned participants: 60
  • From 27 Jun 2025 to the primary completion date, 27 Dec 2026
  • 7 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Received music therapy (MT) in the past year
  • Initiation or altered dose of sedative, stimulant, or anti-cholinergic medications in the past month or plan to initiate these medications during the study, as these are known to impact cognitive function

Other illness

  • Less than 3 months since completion of surgery, radiation, induction chemotherapy (for newly diagnosed or relapsed disease), transplantation, or immunotherapy (e.g., CAR T-Cell, bispecific antibodies)
    • If there is a defined treatment period, the patient must be at least 3 months from treatment completion
    • If the patient is on continuous therapy, patient must have completed at least 6 months of the therapy
    • Maintenance therapies are allowed
  • BOMC score ≥10 (indicative of dementia)

Other

  • Current music training, \>6 months of music training in the past 10 years, or plan to initiate music training during the study
  • No access to an internet-connected device
  • Active suicidal ideation, bipolar, schizophrenia, or substance abuse
  • Uncorrectable visual, auditory, or motor impairments
  • Initiation of any other interventions for CRCD (e.g., cognitive rehabilitation) in the past month or plan to initiate these interventions during the study, as these are known to impact cognitive function

Who the study is looking for

  • English-proficient, aged 18 or older
  • Diagnosis of lymphoma, leukemia, or myeloma
  • Stable oncologic disease or no evidence of disease as indicated in the medical chart or by the oncology team
  • Score of \<54 on the FACT-Cog PCI subscale
  • Minimum life expectancy of one year as per clinician assessment
  • Patient should be able to understand and complete all study assessments on their own.
  • Eligible patient should be able to understand informed consent and provide signed informed consent in English.

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (7)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
Coordinator of this site? Confirm its status
Basking RidgeUnited StatesRecruiting
Memorial Sloan Kettering Cancer Center Suffolk - Commack (All Protocol Activities)
Coordinator of this site? Confirm its status
CommackUnited StatesRecruiting
Memorial Sloan Kettering Westchester (All Protocol Activities)
Coordinator of this site? Confirm its status
HarrisonUnited StatesRecruiting
Memorial Sloan Kettering Monmouth (All Protocol Activities)
Coordinator of this site? Confirm its status
MiddletownUnited StatesRecruiting
Memorial Sloan Kettering Bergen (All Protocol Activities)
Coordinator of this site? Confirm its status
MontvaleUnited StatesRecruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
Coordinator of this site? Confirm its status
New YorkUnited StatesRecruiting
Memorial Sloan Kettering Nassau (All Protocol Activities)
Coordinator of this site? Confirm its status
UniondaleUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.