NCT07053982RecruitingPhase 2
Use of a New Diagnostic Tool in the Detection and Characterization of Endometriosis Lesions
18F]-FES PET in the Detection and Characterization of Endometriosis Lesions
Source: ClinicalTrials.gov · Last updated 25 Mar 2026
Brief summary (registry, in English)
Diagnostic wandering is one of the characteristics of endometriosis due to great anatomical and clinical variability but also due to poorly relevant diagnostic examinations. \[18F\]-FES PET/CT could on the one hand improve diagnosis by showing greater sensitivity than MRI and on the other hand make it possible to quantify and characterize the expression of ER from diagnosis and thus helping to guide therapeutic care. We will thus attempt to correlate the intensity of \[18F\]-FES PET/CT with the expression of estrogen receptors and the intensity of pain.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 10 Jun 2025
- Start date
- 23 Mar 2026
- Primary completion date
- Mar 2028
- Lead sponsor
- University Hospital, Toulouse
- Diseases
- Endometriosis
- NCT number
- NCT07053982
- EU CT number
- 2025-520637-24-00
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 20
- From 23 Mar 2026 to the primary completion date, Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patient treated for endometriosis without surgery;
- Patient taking hormone therapy
Other illness
- Hypersensitivity to the active substance (Fluoroestradiol (18F)) or to any of the excipients
Other
- Pregnant patient
- Menopausal patient
- Patient under legal protection
- Claustrophobic patient
Who the study is looking for
- Cases:
- \- Painful patients with a VAS ≥ 4 treated surgically for painful symptoms related to endometriosis;
- Controls:
- Patient with a VAS \< 4 treated surgically for endometriosis in the context of infertility;
- Age \> 18 years;
- Patient who provided informed consent;
- Patients who underwent a preoperative MRI and were not contraindicated for \[18F\]-FES PET/CT;
- Patient who underwent surgery mid-cycle;
- Affiliation to a social security scheme
Age in the registry: 18 years to 64 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier Universitaire De Toulouse Coordinator of this site? Confirm its status | Toulouse Cedex 9 | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.