NCT07055776Active, not recruiting
Compare the Effectiveness of nVNS and TENS on Pain and Quality of Life in Patients of Migraine
Compare the Effectiveness of Non-invasive Vagus Nerve Stimulation (nVNS) and Non-invasive Transcutaneous Electrical Nerve Stimulation (TENS) on Pain and Quality of Life (QOL) in Patients of Migraine: a Randomized Control Trial
Source: ClinicalTrials.gov · Last updated 9 Jul 2025
Brief summary (registry, in English)
Migraine is a genetically influenced complex neurological disorder characterized by episodes of moderate-to-severe headaches, typically unilateral and frequently accompanied by nausea and heightened sensitivity to light and sound. The common type of migraine headaches is migraine without aura. Migraine has an approximate prevalence of 14.7%, making it the third most common disease in the world. This study aims to compare the effectiveness of non-invasive vagus nerve stimulation (nVNS) and non-invasive transcutaneous electrical nerve stimulation (TENS) in managing pain and improving quality of life (QOL) in patients with migraine.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 72 (actual)
- First submitted
- 28 Jun 2025
- Start date
- 17 Mar 2025
- Primary completion date
- 1 Sept 2025
- Lead sponsor
- Superior University
- Diseases
- Migraine
- NCT number
- NCT07055776
What you commit to
- Study type: Interventional
- Participants enrolled: 72
- From 17 Mar 2025 to the primary completion date, 1 Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- individuals with excessive use of pain medications, recent preventive treatments, or previous surgeries and procedures related to migraines will not be eligible.
Other illness
- Participants with a history of secondary headaches,
- substance abuse, cardiovascular or cerebrovascular disease
- uncontrolled hypertension, psychiatric disorders,
- pregnancy, steroid use, botulinum toxin injections in the past 6 months, or certain other medical conditions were excluded.
Other
- aneurysms, brain tumors, significant head trauma
Who the study is looking for
- People will be eligible for participation of 18-75 years of age.
- Participants are included with previous diagnosis of migraine with aura according to ICHD-3 beta criteria.
- Patients who had 15 headache days per month over the last 6 months will be included in this study.
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chaudary Muhammad Akram Teaching Hospital, Azra Naheed Medical College, Superior University Coordinator of this site? Confirm its status | Lahore | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.