NCT07056049Recruiting
The Efficacy of Additional Motor Training Dosage During the Early Stages Post Stroke on the Upper Extremity Recovery
Efficacy of High-dosage, High-intensity Rehabilitation Program on the Motor Recovery After Stroke in Subacute Patients
Source: ClinicalTrials.gov · Last updated 17 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Intervention abstract Background: Stroke is the leading cause of long-term disability, and the second leading cause of death in the western world. Most stroke survivors will suffer from motor and cognitive disturbances for the rest of their life, which negatively affects their normal daily life. Despite the decline in stroke-related mortality over the past decades, the outcome of rehabilitation programs does not improve, and is predictable regardless of the program used. Still, several human and animal studies show that high capacity of training in the early stages post stroke improve motor recovery. This notion is far from being well established. Aim: Studying the effect of high-dosage, high-intensity training program in the subacute period on upper extremity motor recovery. Population: Stroke survivors. Study duration: 6 months. Study protocol: Participants will receive additional technology-based upper extremity training for 120 min/day, 5d/w, 4 weeks. They will be monitored pre and post training, and 6 months post-stroke. Outcome measures will include clinical, kinematic and adherence measures (see complete list in the protocol).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 10 Jun 2025
- Start date
- 13 Jul 2025
- Primary completion date
- 15 Jan 2027
- Lead sponsor
- Adi Negev-Nahalat Eran
- Diseases
- Stroke
- NCT number
- NCT07056049
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 13 Jul 2025 to the primary completion date, 15 Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cognitive or communication impairments as determined by the clinical team Unstable medical conditions
Other
- A painful shoulder limiting an active forward reach
- Severe spasticity or non-neural loss of range of motion
Who the study is looking for
- Age ≥18 years
- Ischemic or hemorrhagic stroke (hemispheric or brainstem) confirmed by CT or MRI
- First-ever stroke or previous stroke with no upper extremity weakness
- 1 week ≤ Time after stroke onset ≤ 6 weeks
- Active shoulder flexion of at least 20◦ and partial wrist and/or finger active movement
- Ability to provide inform consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Adi-Negev Nahalat Eran Coordinator of this site? Confirm its status | Ofakim | Israel | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.