NCT07057713Not yet recruiting
Total Arterial vs. Mixed Grafting in Left Coronary CABG
A Prospective, Randomized, Double-Blind Controlled Trial Comparing Total Arterial Grafting Versus Conventional Mixed Grafting in the Left Coronary Artery System During Coronary Artery Bypass Grafting (CABG)
Source: ClinicalTrials.gov · Last updated 23 Apr 2026
Brief summary (registry, in English)
This is a prospective, randomized, double-blind controlled trial comparing the clinical efficacy of total arterial grafting (internal thoracic artery and radial artery) versus conventional mixed grafting (internal thoracic artery and great saphenous vein) in the left coronary artery system during coronary artery bypass grafting (CABG). A total of 400 patients undergoing elective CABG at the Second Hospital of Jilin University will be enrolled and randomized into two groups. The primary endpoint is graft patency at 12 months postoperatively, evaluated by coronary angiography or CT angiography. Secondary outcomes include perioperative complications, major adverse cardiovascular events (MACE), and long-term clinical prognosis. The study aims to provide evidence-based guidance on optimal graft selection in CABG.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 400 (estimated)
- First submitted
- 29 Jun 2025
- Start date
- 1 Aug 2026
- Primary completion date
- 1 Aug 2027
- Lead sponsor
- Second Hospital of Jilin University
- Diseases
- Coronary artery disease
- NCT number
- NCT07057713
What you commit to
- Study type: Interventional
- Planned participants: 400
- From 1 Aug 2026 to the primary completion date, 1 Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Scheduled for concurrent cardiac procedures (e.g., valve surgery, congenital heart disease repair, aortic dissection surgery, atrial fibrillation ablation)
- Acute myocardial infarction within 72 hours prior to surgery
- History of prior CABG or other cardiac surgery
Other illness
- History of intracranial hemorrhage or ischemic stroke within the past 14 days
- Severe hepatic or renal insufficiency
Other
- Severe stenosis of left or right subclavian artery
- Unsuitable saphenous veins (e.g., bilateral varicosities)
- Unsuitable radial artery as assessed preoperatively
Who the study is looking for
- Age ≥ 18 years
- Diagnosed with multivessel coronary artery disease
- Indicated for elective coronary artery bypass grafting (CABG) involving ≥3 coronary vessels
- Right coronary artery stenosis \>75%
- Able and willing to provide written informed consent
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Second Hospital of Jilin University Coordinator of this site? Confirm its status | Changchun | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.