NCT07057999Completed

Investigation of the Effect of the MIND Diet on Disease Symptoms in Patients With MS

Effects of the MIND Diet on Fatigue, Quality of Life, and Brain Fog in Patients With Multiple Sclerosis: A Randomized Controlled Trial

Source: ClinicalTrials.gov · Last updated 6 Feb 2026

Brief summary (registry, in English)

The planned parallel group, randomized controlled study design will be used to determine the effects of the MIND diet applied to MS patients on fatigue, quality of life, technological function and brain fog and to contribute to the scientific literature. This study document will also determine the scope of the MIND diet for MS details. The regular questions it aims to answer are as follows: * Is the MIND diet applied to MS treatments effective on quality of life compared to traditional healthy nutrition? * Is the MIND diet applied to MS treatments effective on fatigue compared to traditional healthy nutrition therapy? * Is the MIND diet applied to MS treatments effective on brain fog compared to traditional healthy nutrition therapy? In this study, the MIND diet will be controlled with a traditional healthy nutrition program specific to Türkiye to evaluate the effect of the MIND diet on MS disease. Participants: * Adhere to your specially prepared diet for 3 months * Participate in online meetings with researchers every week to check compliance with the diets * Visit the hospital for a check-up at the end of 3 months The collected study data will be analyzed in a computer environment using the Statistical Package for Social Sciences (IBM, SPSS, version 29.0) software, and p\<0.05 is accepted as the significance level.

Status (registry): Completed
Study type: Interventional
Enrollment: 62 (actual)
First submitted: 18 Jun 2025
Start date: 16 Jun 2025
Primary completion date: 27 Nov 2025
Lead sponsor: Betul Uner
Diseases: Multiple sclerosis
NCT number: NCT07057999

What you commit to

Study type: Interventional
Participants enrolled: 62
From 16 Jun 2025 to the primary completion date, 27 Nov 2025
1 site in 1 country
Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

Having had an attack and/or receiving steroid treatment in the last month

Other illness

Having another chronic metabolic disease and/or having had surgery in the last 3 months

Other

MS patients who are pregnant or lactating
MS patients with limb deficiency
MS patients on a special diet
Patients using antidepressants and/or mood stabilizers

Who the study is looking for

Adult MS patients between the ages of 18-65 diagnosed according to the 2017 McDonald criteria
Having been diagnosed with MS at least three months ago; patients are called for routine check-ups in the first and third months after starting treatment, as liver function tests and/or hemogram values may be impaired due to the treatment they started when they are newly diagnosed with MS. For this reason, it was planned to include patients whose check-ups were completed and no unexpected changes were observed in the blood parameters table due to the medication.
No DMT change in the last 6 months
Patients who use their medications regularly
Not using nutritional support or supplements
Patients with an EDSS score of ≤6
Patients with a body mass index (BMI) between 18.5-24.9 kg/m2

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

Site	City	Country	Site status
Muğla Sıtkı Koçman University/Muğla Training and Research Hospital Neurology Polyclinic Coordinator of this site? Confirm its status	Muğla	Turkey (Türkiye)	Unknown status

This page is information, not medical advice. Discuss any trial with your doctor.