NCT07058389Recruiting
Synergy Between Physical Activity and Outdoor Green Environments to Reduce the Intensity of Negative Symptoms in Schizophrenia.
Synergy Between Physical Activity and Outdoor Green Environments to Reduce the Intensity of Negative Symptoms in Schizophrenia: a Pilot Study.
Source: ClinicalTrials.gov · Last updated 25 Nov 2025
Brief summary (registry, in English)
Physical activity appears to be a novel and original adjunctive therapeutic approach in the management of patients with schizophrenia. It may help reduce schizophrenic symptoms, act as a pro-cognitive therapy, improve quality of life, and reduce cardiovascular comorbidities. Moreover, some evidence suggests that physical activity practiced in a natural environment has even more positive effects on mental health compared to physical activity carried out indoors or in urban settings. Indeed, greater exposure to greenery is associated with a better perception of general health and with reduced levels of cortisol, anxiety, and depression. No study has yet attempted to examine the impact of physical activity in green (outdoor) spaces compared to indoor physical activity on the negative symptoms of patients suffering from schizophrenia. The aim of this study is therefore to test this hypothesis.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 45 (estimated)
- First submitted
- 30 Jun 2025
- Start date
- 7 Oct 2025
- Primary completion date
- Jun 2027
- Lead sponsor
- Centre Hospitalier Universitaire de Saint Etienne
- Diseases
- Schizophrenia
- NCT number
- NCT07058389
What you commit to
- Study type: Interventional
- Planned participants: 45
- From 7 Oct 2025 to the primary completion date, Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any subject with chronic joint pathologies (example: repeated sprains, patellar or ligament problems) or cardiac pathologies.
- Subject unable to understand the purpose and conditions of the study, unable to give consent.
Other
- Patient unsuitable for study in the opinion of the investigator
- Any subject presenting chronic or central neurological pathologies.
- Any subject deprived of liberty or subject to legal protection
- Excessive consumption of alcohol (\> 14 glasses per week) or caffeinated drinks (\> 400 mg of coffee per day).
- Pregnant women.
Who the study is looking for
- Patients with schizophrenia, aged 18 to 55 years
- Having persistent negative symptoms (SNS), negative symptoms self-assessment scale \> 7
- Regularly monitored in the psychiatry department.
- Have no medical contraindications to physical activity
- Subject affiliated with or entitled to a social security system.
- Subject having received informed information about the study and having co-signed, with the investigator, consent to participate in the study.
- Male or female.
Age in the registry: 18 years to 55 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chu de Saint Etienne Coordinator of this site? Confirm its status | Saint-Etienne | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.