NCT07059208Not yet recruiting
Atrioventricular Nodal Ablation Versus Pulmonary Vein Isolation - Patient Centred Decisions
Source: ClinicalTrials.gov · Last updated 14 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this clinical trial is to compare two procedural approaches to managing atrial fibrillation. The main questions it aims to answer are: Is AF ablation or pacemaker implant and AV nodal ablation a more effective treatment approach for patients with atrial fibrillation refractory to pharmacological treatment? What effect do these differing treatment approaches have on patient's quality of life and mental health? Participants will: Be randomly allocated to one of the treatment approaches. Visit the clinic 2 months, 12 months and 24 months after their procedure for a checkup, questionnaires and repeat heart ultrasounds.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 172 (estimated)
- First submitted
- 1 Jul 2025
- Start date
- Sept 2025
- Primary completion date
- Sept 2029
- Lead sponsor
- Sunshine Coast Hospital and Health Service
- Diseases
- Atrial fibrillation
- NCT number
- NCT07059208
What you commit to
- Study type: Interventional
- Planned participants: 172
- From Sept 2025 to the primary completion date, Sept 2029
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous pulmomary vein isolation, left atrial flutter ablation or atrioventricular node ablation.
- Not suitable for pulmonary vein isolation and/or pacemaker implant on clinical grounds.
Other
- BMI \>40.
Who the study is looking for
- Age greater than 65 years for patients with persistent atrial fibrillation or greater than 75 years for patients with paroxysmal atrial fibrillation.
- Unsuccessful trial of at least one pharmacological rate or rhythm control medication. This includes patients with medication refractory AF and/or intolerance to the medication(s).
- A resting ECG demonstrating AF with ventricular response rate \>70bpm on a pharmacological rate control medication, or \>90bpm while not on rate control medication.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.