NCT07060885CompletedPhase 3
A Research Study of House Dust Mite (HDM) SLIT-tablet for the Treatment of HDM Allergy in Chinese Participants Aged 12-65
A Randomised Double-blind Placebo-controlled Phase III Field Trial Evaluating the Efficacy and Safety of the House Dust Mite (HDM) SLIT-tablet in Chinese Participants Aged 12-65 Years With HDM Allergic Rhinitis/Rhinoconjunctivitis With or Without Asthma
Source: ClinicalTrials.gov · Last updated 5 Oct 2026
Brief summary (registry, in English)
A research study of house dust mite (HDM) SLIT-tablet for the treatment of HDM allergy in Chinese participants aged 12-65.
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 327 (actual)
- First submitted
- 1 Jul 2025
- Start date
- 1 Sept 2025
- Primary completion date
- 31 Aug 2026
- Lead sponsor
- ALK-Abelló A/S
- Diseases
- Asthma
- NCT number
- NCT07060885
- EudraCT number
- 2025-000321-14
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 327
- From 1 Sept 2025 to the primary completion date, 31 Aug 2026
- 30 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Asthma requiring treatment with high dose of inhaled corticosteroid
Other illness
- Any nasal or pharyngeal condition that could interfere with the safety or efficacy evaluation
- A relevant history of systemic allergic reaction
Other
- Sensitised and regularly exposed to perennial allergens
Who the study is looking for
- Male or female Chinese subjects aged 12-65 years
- A clinical history of HDM AR/C (Allergic rhinitis/rhinoconjunctivitis) (with or without asthma) and with allergic rhinitis symptoms despite having received allergy pharmacotherapy during the previous year prior to screening
- Have a certain level of AR (Allergic rhinitis) symptoms on at least 8 of the last 14 days of the baseline period
- Use symptomatic medication for treatment of HDM allergic rhinitis during at least 8 of the last 14 days of the baseline period
- Positive skin prick test (SPT) and IgE (Immunoglobulin E) to D. pteronyssinus or D. farinae at screening
- Lung function ≥ 70% of predicted value
Age in the registry: 12 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (30)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Peking Union Medical College Hospital Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
| Beijing Tongren Hospital, Capital Medical University Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
| The Third Hospital of Changsha - Pulmonology Coordinator of this site? Confirm its status | Changshacun | China | Unknown status |
| Sichuan University - West China Second University Hospital (WCSUH) (West China Women's and Children's Hospital) Coordinator of this site? Confirm its status | Chengdu | China | Unknown status |
| West China Hospital of Sichuan University - Otorhinolaryngology Coordinator of this site? Confirm its status | Chengdu | China | Unknown status |
| The First Affiliated Hospital of Chongqing Medical University - Respiratory Coordinator of this site? Confirm its status | Chongqing | China | Unknown status |
| Fujian Provincial Hospital Coordinator of this site? Confirm its status | Fuzhou | China | Unknown status |
| The first hospital affiliated Fujian medical University Coordinator of this site? Confirm its status | Fuzhou | China | Unknown status |
| The first affiliated hospital of guangzhou medical university-respiratory department Coordinator of this site? Confirm its status | Guangzhou | China | Unknown status |
| The Third Affilliated Hospital of Southern Medical University Coordinator of this site? Confirm its status | Guangzhou | China | Unknown status |
| The Third Affiliated Hospital,Sun Yat-Sen University Coordinator of this site? Confirm its status | Guangzhou | China | Unknown status |
| Hainan General Hospital - Respiratory Coordinator of this site? Confirm its status | Haikou | China | Unknown status |
| Zhejiang Provincial People's Hospital Coordinator of this site? Confirm its status | Hangzhou | China | Unknown status |
| The First Affiliated Hospital of University of South China - Endocrinology Coordinator of this site? Confirm its status | Hengyang | China | Unknown status |
| Jingzhou Central Hospital - Otorhinolaryngology Coordinator of this site? Confirm its status | Jingzhou | China | Unknown status |
| The Second Affiliated Hospital of Nanchang University Coordinator of this site? Confirm its status | Nanchang | China | Unknown status |
| Nanchang University - The First Affiliated Hospital Coordinator of this site? Confirm its status | Nanchang | China | Unknown status |
| Jiangsu Province Hospital/ The First Affiliated Hospital with Nanjing Medical University - Otorhinolaryngology Coordinator of this site? Confirm its status | Nanjing | China | Unknown status |
| The People's Hospital of Guangxi Zhuang Autonomous Region - Nephrology - Oncology Coordinator of this site? Confirm its status | Nanning | China | Unknown status |
| The First Affiliated Hospital of Guangxi Medical University Coordinator of this site? Confirm its status | Nanning | China | Unknown status |
| Shanghai Jiaotong University School of Medicine Ruijin Hospital Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
| Zhongshan Hospital Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
| Huazhong University of science and Technology Union Shenzhen Hospital(Nanshan Hospital) - Endocrinology Coordinator of this site? Confirm its status | Shenzhen | China | Unknown status |
| Shenzhen Children's Hospital - Respiratory Coordinator of this site? Confirm its status | Shenzhen | China | Unknown status |
| The First Affiliated Hospital of Soochow University - Respiratory Coordinator of this site? Confirm its status | Suzhou | China | Unknown status |
| The 2nd School of Medicine, WMU/The 2nd Affiliated Hospital and Yuying Children's Hospital of WMU - Pediatrics Coordinator of this site? Confirm its status | Wenzhou | China | Unknown status |
| Union Hospital Tongji Medical College Huazhong University of Science and Technology - Oncology Coordinator of this site? Confirm its status | Wuhan | China | Unknown status |
| Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology Coordinator of this site? Confirm its status | Wuhan | China | Unknown status |
| The Second Affiliated Hospital of Xi an Jiaotong University (Xibei Hospital) - Nephrology Coordinator of this site? Confirm its status | Xi'an | China | Unknown status |
| The Fifth Affiliated Hospital of Sun Yat-Sen University - University Hospital Coordinator of this site? Confirm its status | Zhuhai | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.