NCT07065955Completed
Longevity Diet and the Fasting-mimicking Diet
Effects of the Longevity Diet and the Fasting-mimicking Diet on Body Composition, Risk Factors for Age-related Diseases
Source: ClinicalTrials.gov · Last updated 15 Jul 2025
Brief summary (registry, in English)
This retrospective clinical study examines the impact of the longevity diet and fasting-mimicking diet (FMD), either alone or combined, on body composition and health indicators. Focused on subjects from the Valter Longo Foundation (2019-2024), the study aims to evaluate their effects on body fat percentage, lean mass, muscle function, and lipid profiles. The longevity diet, rooted in centenarian dietary traditions, emphasizes isocaloric meals with a balance of complex carbohydrates, unsaturated fats, and plant-based proteins. FMD involves a 5-day highly hypocaloric vegan diet to simulate fasting benefits. Hypothesizing that a return to a modified Mediterranean diet or incorporating FMD could improve overall health, the study spans diverse cohorts based on intervention type, duration, obesity level, and physio-pathological status. Data, collected from electronic medical records, will undergo statistical analyses to compare pre- and post-intervention measurements, exploring outcomes across subgroups. Ethical considerations, including de-identified data and informed consent, ensure compliance with clinical research regulations. In conclusion, this study provides valuable insights into the potential health and longevity benefits of the longevity diet and FMD, with implications for public wellness.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 365 (actual)
- First submitted
- 17 Mar 2025
- Start date
- 1 Jan 2019
- Primary completion date
- 1 Mar 2024
- Lead sponsor
- Fondazione Valter Longo
- Diseases
- Obesity
- NCT number
- NCT07065955
What you commit to
- Study type: Observational
- Participants enrolled: 365
- From 1 Jan 2019 to the primary completion date, 1 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Age \< 18 years;
Other
- Lack of informed consent or privacy;
- Women who are pregnant or breastfeeding;
- Patients affected by oncological and/or neurodegenerative pathologies.
Who the study is looking for
- Healthy patients and/or those with diseases, excluding neoplastic and neurodegenerative pathologies;
- Age \>/= 18 years;
- Body mass index \>/= 18.5 kg/m2;
- At least two visits, both characterized by bioimpedance and anthropometric analysis;
- At least 3 months between the first and last bioimpedance and anthropometric analysis;
- Signature of informed consent and privacy for the conducted visits.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fondazione Valter Longo Onlus Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.