NCT07067632Completed
Mortality Outcome of Controlled Blood Pressure Participants
Mortality Outcome of Controlled Hypertension in Randomized Controlled or Open-label Study Intentionally Directed Intervention Effect Blood Pressure: A Systematic Review and Meta-Analysis
Source: ClinicalTrials.gov · Last updated 4 Nov 2026
Brief summary (registry, in English)
Despite advances in antihypertensive therapy, some patients with well-controlled blood pressure still experience fatal outcomes. This paradox raises critical questions about the efficacy of blood pressure-targeted interventions and whether BP control alone ensures survival. This systematic review and meta-analysis aims to evaluate all-cause mortality and cardiovascular death among hypertensive patients who achieved BP targets in RCTs or open-label trials. To determine whether achieving controlled blood pressure through intentional intervention (pharmacological or procedural) in RCTs or open-label studies reduces mortality (all-cause and cardiovascular) in hypertensive patients.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 246587 (actual)
- First submitted
- 6 Jul 2025
- Start date
- 1 Jul 2025
- Primary completion date
- 29 Sept 2026
- Lead sponsor
- DejthidaNathaphong
- Diseases
- High blood pressure
- NCT number
- NCT07067632
What you commit to
- Study type: Observational
- Participants enrolled: 246587
- From 1 Jul 2025 to the primary completion date, 29 Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Observational or retrospective studies
- Pediatric or pregnant participants
- Case reports, editorials, or conference abstracts without full data
- Studies not reporting mortality outcomes separately for controlled BP
Who the study is looking for
- Adults ≥18 years with diagnosed hypertension
- Blood pressure controlled at target values defined by the study (e.g., \<140/90 mmHg or \<130/80 mmHg)
- Any comorbidity allowed unless the study focuses on pregnancy or pediatric population
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nathaphong Coordinator of this site? Confirm its status | Bangkok | Thailand | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.