NCT07069244Completed
Investigation of the Relationship Between Periodontitis and Alzheimer's Disease in Terms of Blood Parameters
Blood Markers in Periodontal Inflammation and Alzheimer's Disease: A Retrospective Case-Control Study
Source: ClinicalTrials.gov · Last updated 17 Nov 2025
Brief summary (registry, in English)
The aim of this study was to analyse the possible relationship between periodontal inflammation and Alzheimer's disease and to investigate the role of blood parameters in this relationship.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 100 (actual)
- First submitted
- 5 Jul 2025
- Start date
- 5 Aug 2025
- Primary completion date
- 3 Oct 2025
- Lead sponsor
- Uskudar University
- Diseases
- Alzheimer disease
- NCT number
- NCT07069244
What you commit to
- Study type: Observational
- Participants enrolled: 100
- From 5 Aug 2025 to the primary completion date, 3 Oct 2025
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Individuals who regularly use anti-inflammatories or corticosteroids
Other illness
- Individuals with uncontrolled systemic disease,
Other
- Individuals with fewer than 10 teeth,
Who the study is looking for
- Between March 2022 and July 2025, those who applied to the Periodontics Departments of the Dentistry Faculties of Uskudar University, Bezmialem Vakif University and Bolu Abant Izzet Baysal University,
- Informed consent form was obtained during the examination,
- Over 50 years of age,
- Non-smoker and non-alcoholic,
- No psychiatric disorders affecting cognitive status and no medication affecting cognitive status,
- Complete blood count was performed within the 6 months prior to the date of inclusion in the study,
- No dental treatment within the last 1 year,
- Periodontal examination was performed by expert periodontologists who calibrated the inter- and intra-examination,
- Individuals diagnosed with periodontitis as a result of periodontal examination and radiographic examination, and
- For individuals diagnosed with Alzheimer's disease: Recording their stage according to the Clinical Dementia Rating (CDR) and Standardized Mini-Mental Test (SMMT) scores
Age in the registry: 50 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bolu Abant Izzet Baysal University Coordinator of this site? Confirm its status | Bolu | Turkey (Türkiye) | Unknown status |
| Uskudar University Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
| Bezmialem Vakif University Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.