NCT07070583Recruiting
Impact of Aorto-Iliac Occlusive Disease Treatment on Blood Pressure
Impact of Endovascular Treatment of Aorto-iliac Disease on Systemic Hypertension A Pilot Study Impact of Aorto-Iliac Occlusive Disease Treatment on Blood Pressure
Source: ClinicalTrials.gov · Last updated 3 Apr 2026
Brief summary (registry, in English)
Hypertension is a major risk factor for a variety of cardiovascular diseases. When hypertension results from increased vascular resistance due to a narrowing of the descending aorta, it can be effectively treated with stenting. More recently, evidence suggest that stenting in more distal parts of the arterial vascular bed is also associated with a reduction in blood pressure. The investigators hypothesize that stenting of occlusions more distal of the descending aorta decreases the central blood pressure and afterload as reflected by NT-proBNP (N-terminal pro-Brain Natriuretic Peptide), a biomarker of intracardiac pressures and predictor of heart failure events. The goal of this pilot study is to prospectively investigate changes in blood pressure after stent placement in the aorto-iliac region.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 30 Jun 2025
- Start date
- 30 Mar 2026
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Rijnstate Hospital
- Diseases
- High blood pressure
- NCT number
- NCT07070583
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 30 Mar 2026 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Acute occlusion of the target area (Acute Leriche Syndrome)
- Embolic disease
Other
- Patient is unable to understand the study requirements and/ or is unwilling to adhere to the follow-up
- Juxtarenal pathology (\<2cm below the lowest renal artery)
Who the study is looking for
- Age ≥18 years
- Singed informed consent
- Chronic occlusion in the infrarenal aorta and/or one or both common iliac arteries
- Total lesion length of ≥30mm
- Clinical indication for treatment of the pathology (Chronic limb threatening ischemia or disabling intermittent claudication not responding to supervised exercise training)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rijnstate Coordinator of this site? Confirm its status | Arnhem | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.