NCT07074704Enrolling by invitation
tACS to Improve Negative Symptoms & Cognition in Long-term Hospitalized Schizophrenia Patients.
Transcranial Alternating Current Stimulation (tACS) as an Augmentation Treatment for Negative Symptoms and Cognitive Deficits in Long-term Hospitalized Schizophrenia Patients
Source: ClinicalTrials.gov · Last updated 24 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study aims to evaluate the efficacy of transcranial alternating current stimulation (tACS) on negative symptoms and cognitive function in long-term hospitalized patients with schizophrenia. At the same time, this study will explore the potential impact of relevant biomarkers and genetic factors on the efficacy of tACS intervention.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 23 Jun 2025
- Start date
- 11 Jun 2025
- Primary completion date
- 5 Feb 2026
- Lead sponsor
- Tongji University
- Diseases
- Schizophrenia
- NCT number
- NCT07074704
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 11 Jun 2025 to the primary completion date, 5 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of other drugs that affect the results during the study, such as benzodiazepines, non-benzodiazepine sedatives, and psychostimulants
- Patients with alcohol, drugs Abuse history
- Patients who have received TACS treatment in the past and have no effect or intolerance
- During the study, drugs that affect the results were used in combination, such as benzodiazepines, non-benzodiazepine sedatives, and psychostimulants
Other illness
- Combined diagnosis of other mental illnesses in DSM-5
- History of severe neurological diseases, epilepsy, craniocerebral trauma, etc.
- Severe organic diseases of the heart, liver, kidney and other organs that are unstable
- Infectious skin diseases
- Patients with a history of severe neurological diseases, epilepsy, craniocerebral trauma, etc.
- Patients with severe organic diseases that cause instability of organs such as heart, liver, and kidney
- Patients with infectious skin diseases
- Patients with a history of alcohol and drug abuse -
Other
- Pregnant or lactating women
- Patients with claustrophobia
- Pregnant or lactating women
- Patients with claustrophobia
Who the study is looking for
- Inclusion criteria for long-term hospitalized schizophrenia patients:
- Diagnosed with DSM-5 schizophrenia and hospitalized for more than half a year
- Aged between 18 and 65 years old
- Willing to participate in the study and sign the informed consent
- Stable condition, PANSS total score changed less than 15% at least 2 months before the study.
- Education level above primary school
- Normal vision or normal after correction
- No diagnosed mental illness
- Aged between 18 and 65 years old
- Willing to participate in the study and sign the informed consent
- Education level above primary school
- Normal vision or normal after correction
- Residents living in Pudong community
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shanghai Pudong New Area Mental Health Center Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.