NCT07077031Completed
Comparison of Two Magnesium Sulfate Protocols in Opioid-Free Anesthesia for Bariatric Surgery
Comparison of Postoperative Morphine Requirements Between Two Magnesium Sulfate Administration Protocols in Opioid-Free Anesthesia for Bariatric Surgery
Source: ClinicalTrials.gov · Last updated 22 Jul 2025
Brief summary (registry, in English)
This retrospective observational study aims to compare postoperative morphine consumption in patients undergoing bariatric surgery with opioid-free anesthesia (OFA) using two different intravenous magnesium sulfate administration protocols: a single bolus versus a bolus followed by continuous infusion. Medical records of 110 patients operated between June 2022 and December 2023 at Hospital HM Nou Delfos were reviewed. All patients received standardized OFA, and only the magnesium protocol varied between the groups. The primary objective was to evaluate total morphine consumption during the first 48 hours postoperatively. Secondary outcomes included pain scores, antiemetic use, and adverse events. This study was approved by the hospital's Research Ethics Committee (Protocol V3\_12.05.2025).
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 110 (actual)
- First submitted
- 11 Jul 2025
- Start date
- 1 Jun 2022
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- Hospital HM Nou Delfos
- Diseases
- Obesity
- NCT number
- NCT07077031
What you commit to
- Study type: Observational
- Participants enrolled: 110
- From 1 Jun 2022 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Chronic opioid use before surgery
Other illness
- Severe renal or hepatic insufficiency
- Uncontrolled psychiatric disorders
Lab values
- Known allergy to magnesium sulfate or any drug used in the anesthetic protocol
Other
- Pregnancy or breastfeeding
- Untreated coagulopathy
- Active substance abuse
- Intraoperative complications requiring deviation from the protocol
- Postoperative morphine consumption exceeding institutional standards
Who the study is looking for
- Age between 18 and 65 years
- Body mass index (BMI) ≥ 30 kg/m²
- ASA physical status II or III
- Underwent laparoscopic bariatric surgery (sleeve gastrectomy or Roux-en-Y gastric bypass) under opioid-free total intravenous anesthesia
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital HM Nou Delfos Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.