NCT07082231Not yet recruiting
Cohort of Patients With Ulcerative Colitis or Polyps Followed in CHU de Bordeaux Associated With a Biocollection - COLIBRI
Source: ClinicalTrials.gov · Last updated 24 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Ulcerative colitis (UC) is a chronic disease characterized by acute episodes of bloody diarrhea with varying degrees of severity. The most feared event, acute severe UC, can lead to life-threatening and systemic complications. Little is known about the determinants of severity in UC. The investigators hypothesize that distinct severity phenotypes of UC arise from intricated host-microbiota mechanisms influencing repair mechanisms. Our first and main objective is to study the natural history of UC during a one-year time period in a cohort of patients.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- First submitted
- 12 Mar 2025
- Start date
- Sept 2025
- Primary completion date
- Sept 2027
- Lead sponsor
- University Hospital, Bordeaux
- Diseases
- Ulcerative colitis
- NCT number
- NCT07082231
What you commit to
- Study type: Interventional
- Planned participants: 200
- From Sept 2025 to the primary completion date, Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Inclusion criteria:
- General Inclusion Criteria:
- Patients covered by a social security system.
- French-speaking patients.
- Patients aged ≥18 years.
- Patients who have provided free, informed, and written consent (no later than the inclusion day and before any research-related examination).
- Specific Inclusion Criteria for the UC Group:
- Patients diagnosed with ulcerative colitis (UC) according to the European Crohn's and Colitis Organisation (ECCO) guidelines.
- Patients undergoing lower gastrointestinal endoscopy or rectocolic surgery.
- Non-UC Patients with Polyps Group:
- Patients undergoing colonoscopy with resection of hyperplastic polyps in the rectum, sessile serrated lesions, or adenomas \>2 cm.
- Exclusion criteria:
- Patients with perianal, ileal lesions, or endoscopic features of colonic lesions suggestive of Crohn's disease.
- Pregnant or breastfeeding women.
- Patients under legal protection or unable to provide informed consent.
- Patients deprived of liberty by judicial or administrative decision, hospitalized without consent, or admitted to a healthcare or social institution for reasons unrelated to the study.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Bordeaux Coordinator of this site? Confirm its status | Pessac | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.