NCT07083531Recruiting
Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait
Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait
Source: ClinicalTrials.gov · Last updated 24 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This is a cross-sectional, clinical research study comparing postmenopausal women of African Descent (AD) with different hemoglobin genotypes: normal and sickle cell trait (SCT). This research study has two purposes. The first purpose is to determine whether having SCT is a risk factor for the development of bone thinning in older women. The second purpose is to investigate whether women with SCT have reduced muscle function and increased frailty compared to women without SCT. The investigators estimate enrolling 50 female volunteers who are at least 50 years old and have not had a menstrual period for at least 12 consecutive months. Volunteers need not know whether they have SCT as this will be evaluated as part of the study.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 24 Jun 2024
- Start date
- 23 Aug 2022
- Primary completion date
- 23 Aug 2025
- Lead sponsor
- UConn Health
- Diseases
- Sickle cell disease
- NCT number
- NCT07083531
What you commit to
- Study type: Observational
- Planned participants: 50
- From 23 Aug 2022 to the primary completion date, 23 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking an investigational drug
Other illness
- Taking medications known to influence bone metabolism (e.g., glucocorticoids, hormonal therapy, cancer or chemotherapy meds, anti-resorptive medications or anabolic therapies).
- Known metabolic bone disorder (e.g., uncontrolled thyroid disease, hyperparathyroidism, Vitamin D deficiency)
- Documented sickle cell disease
Who the study is looking for
- Female of African Decent.
- Age 50 years or older.
- Lack of menstrual period for at least 12 consecutive months
Age in the registry: 50 years to - · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UConn Health Coordinator of this site? Confirm its status | Farmington | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.