NCT07084597Recruiting
Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male Parkinson's Disease Patients With Hypovitaminosis D
Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male
Source: ClinicalTrials.gov · Last updated 29 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this clinical trial is to see the effect of vitamin D3 supplementation on cardiac autonomic nerve function in male Parkinson's disease patients with hypovitaminosis D Main questions it aims to answer are: 1. Does vitamin D improves heart rate variability(HRV) in male Parkinson's disease patients ? 2. Does vitamin D improves cardiac autonomic nerve function in male Parkinson's disease patients ? It is a self control trial. Vitamin D3 deficient Parkinson's disease participants will a. undergo through baseline HRV test b. Then they will take vitamin D3 capsule 50000 IU once in a week for 8 consecutive weeks c. Then after intervention with vitamin D supplementation post interventional HRV will be done. Researcher will compare pre intervention(pre test) and post intervention(post test) value of HRV
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 15 (estimated)
- First submitted
- 17 Jul 2025
- Start date
- Jul 2025
- Primary completion date
- Oct 2025
- Lead sponsor
- Bangladesh Medical University
- Diseases
- Parkinson disease
- NCT number
- NCT07084597
What you commit to
- Study type: Interventional
- Planned participants: 15
- From Jul 2025 to the primary completion date, Oct 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients on following drugs will be excluded-
- Antioxidant vitamin supplements
- Lipid lowering medications
- Antihypertensive drug
- Anti-arrhythmic drug
- Sedatives
Other illness
- Patients with a history of drug abuse including alcoholism.
Lab values
- All patients with the history of or clinical manifestation of currently suffering from following diseases \& condition will be excluded
- Severe Cardiovascular disorders
- Severe neurological disorders
- Severe Respiratory disorders
- Severe Renal insufficiency (S. Creatinine \> 1.5 mg/dl, Acute or chronic kidney disease)
- Severe Endocrine disease
- Severe Arthritis
- Severe Liver diseases
- Severe Neoplastic disease
- Severe Psychiatric disorder
- Current use of iron, zinc, calcium, magnesium and multivitamin supplementation
- Already performing yoga or breathing exercise
- Hypercalcemia
Criteria the registry did not label
- IInclusion criteria:
- Male patients with of Parkinson's disease diagnosed by neurologist with unilateral or bilateral involvement and mild to moderate disability according to Hoehn and Yahr (H-Y) scale (I-III)
- Age: 51-70 years
- BMI: 18.5-24.9 kg/m2
- Vitamin D3 deficient or insufficient
- On Levodopa medication
Age in the registry: 51 years to 70 years · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bangladesh Medical University Coordinator of this site? Confirm its status | Dhaka | Bangladesh | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.