NCT07085949Completed
Effect of Different Positive End-Expiratory Pressure (PEEP) Levels on Optic Nerve Sheath Diameter
Evaluation of the Effect of Different Positive End-Expiratory Pressure (PEEP) Levels on Optic Nerve Sheath Diameter in Patients Undergoing Vertebral Surgery; Prospective Observational Study
Source: ClinicalTrials.gov · Last updated 24 Feb 2026
Brief summary (registry, in English)
The goal of this prospective observational study is to evaluate the effects of different PEEP values on the optic nerve sheath diameter (ONSD), a noninvasive indicator of intracranial pressure (ICP), in patients undergoing vertebral surgery. The main question it aims to answer is how mechanical ventilation setting of 5 and 10 cmH2O PEEP effect optic nerve sheath diameter after surgery at extubation.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 105 (actual)
- First submitted
- 17 Jul 2025
- Start date
- 30 Jul 2025
- Primary completion date
- 1 Jan 2026
- Lead sponsor
- Izmir City Hospital
- NCT number
- NCT07085949
What you commit to
- Study type: Observational
- Participants enrolled: 105
- From 30 Jul 2025 to the primary completion date, 1 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Those who have had carotid stenosis or surgery
Other illness
- Congestive heart failure
- Uncontrolled hypertension
- Cerebrovascular disease
Lab values
- Patients were defined as having a hemoglobin concentration below 9 g/dL
Other
- Severe COPD
- Pulmonary edema
- Hemodynamic instability
- Pregnant women
- Those who did not wish to participate in the study.
Who the study is looking for
- Age between 18-65 years
- ASA I, II, III
- Patients undergoing elective vertebral surgery in the prone position
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Izmir City Hospital Coordinator of this site? Confirm its status | Izmir | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.