Fact CheckerSign in

NCT07087431Recruiting

Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health

PROACT 3: Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health

Source: ClinicalTrials.gov · Last updated 23 Mar 2026

Brief summary (registry, in English)

The goal of this clinical trial is to evaluate whether disclosure of a polygenic risk score for coronary artery disease (CAD PRS) influences cardiovascular health and risk factor modification over one year among adults aged 30-75 years in the Mass General Brigham primary care network who are not currently taking LDL cholesterol-lowering medications.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
500 (estimated)
First submitted
20 Jul 2025
Start date
15 Oct 2025
Primary completion date
15 Oct 2026
Lead sponsor
Massachusetts General Hospital
NCT number
NCT07087431

What you commit to

  • Study type: Interventional
  • Planned participants: 500
  • From 15 Oct 2025 to the primary completion date, 15 Oct 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • \- Currently taking LDL cholesterol- lowering medications, including statins

Who the study is looking for

  • Current age 30-75 years
  • Established primary care at Mass General Brigham with at least one visit in the last 2 years

Age in the registry: 30 years to 75 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Massachusetts General Hospital
Coordinator of this site? Confirm its status
BostonUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.