NCT07087431Recruiting
Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health
PROACT 3: Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health
Source: ClinicalTrials.gov · Last updated 23 Mar 2026
Brief summary (registry, in English)
The goal of this clinical trial is to evaluate whether disclosure of a polygenic risk score for coronary artery disease (CAD PRS) influences cardiovascular health and risk factor modification over one year among adults aged 30-75 years in the Mass General Brigham primary care network who are not currently taking LDL cholesterol-lowering medications.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 500 (estimated)
- First submitted
- 20 Jul 2025
- Start date
- 15 Oct 2025
- Primary completion date
- 15 Oct 2026
- Lead sponsor
- Massachusetts General Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT07087431
What you commit to
- Study type: Interventional
- Planned participants: 500
- From 15 Oct 2025 to the primary completion date, 15 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- \- Currently taking LDL cholesterol- lowering medications, including statins
Who the study is looking for
- Current age 30-75 years
- Established primary care at Mass General Brigham with at least one visit in the last 2 years
Age in the registry: 30 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.