NCT07088744Not yet recruiting
Comparison of the Sensitivity of pCLE and Pathological Biopsy Before ESD
Comparison of the Sensitivity of Probe-based Confocal Laser Endomicroscopy and Pathological Biopsy Before Endoscopic Submucosal Dissection
Source: ClinicalTrials.gov · Last updated 28 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Pathological biopsy before endoscopic submucosal dissection (ESD) the gastric lesion plays an important role in differentiating the pathological nature of the lesion and guiding treatment decisions. However, due to the influence of the materials used, the sensitivity of pathological biopsy is not satisfactory. Confocal Laser Endomicroscopy (CLE) is a technology that integrates a confocal microscope into an endoscope. It enables the acquisition of high-resolution microscopic images of the mucosal layer in real-time (with a magnification of up to 1000 times), and it is an optical biopsy technique. It has unique value in the determination of the pathological nature of gastric lesions. The main purpose of this study is to compare the sensitivity of pathological biopsy and CLE in differentiating the pathological nature of gastric lesions.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 169 (estimated)
- First submitted
- 19 Jul 2025
- Start date
- 30 Jul 2025
- Primary completion date
- 31 Aug 2025
- Lead sponsor
- Changhai Hospital
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT07088744
What you commit to
- Study type: Observational
- Planned participants: 169
- From 30 Jul 2025 to the primary completion date, 31 Aug 2025
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe cardiac or pulmonary dysfunction, impaired renal function, coagulopathy, pregnancy or lactation, allergy to fluorescein, and inability to provide informed consent.
Who the study is looking for
- patients aged 18 to 85 years who were scheduled for endoscopic submucosal dissection due to early-stage gastric cancer were consecutively enrolled.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| West China Hospital of Sichuan University Coordinator of this site? Confirm its status | Chengdu | China | Unknown status |
| Guangxi Zhuang Autonomous Region People's Hospital Coordinator of this site? Confirm its status | Nanning | China | Unknown status |
| The First Affiliated Hospital of Naval Medical University Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
| Northern Theater Command Hospital Coordinator of this site? Confirm its status | Shenyang | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.