NCT07089758Not yet recruiting
A Study for Cerebral Open Flow Microperfusion
A Pilot Feasibility Study for Cerebral Open Flow Microperfusion in Patients Undergoing Planned Neurosurgical Resection of Diseased Parenchyma.
Source: ClinicalTrials.gov · Last updated 23 Mar 2026
Brief summary (registry, in English)
The purpose of this study is to evaluate the safety and feasibility of intra-operative microperfusion during a planned neurosurgical resection of diseased brain parenchyma, including either an epileptic focus requiring temporal lobectomy or a glioma. Devices used for microperfusion are Joanneum Research cerebral open flow microperfusion (OFM) catheters, push and pull tubing, and MPP102-II pump.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 6 (estimated)
- First submitted
- 25 Jul 2025
- Start date
- 1 Oct 2026
- Primary completion date
- 29 Feb 2028
- Lead sponsor
- Mayo Clinic
- Diseases
- Glioblastoma
- NCT number
- NCT07089758
What you commit to
- Study type: Interventional
- Planned participants: 6
- From 1 Oct 2026 to the primary completion date, 29 Feb 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who are not appropriate candidates for surgery due to current or past medical history or uncontrolled concurrent illness.
Other
- Vulnerable populations: pregnant women, prisoners or the mentally handicapped.
- Patients whom the surgeon deems to be at increased risk of adverse effects from the study.
Who the study is looking for
- ECOG performance status (PS) 0, 1 or 2.
- Clinical and radiographic evidence diagnosis of glioma, or a prior diagnosis of glioma (suspected WHO grade II-IV), OR clinical evidence of epileptic foci requiring a temporal lobectomy.
- Clinical indication for resection as part of routine clinical care, with plan for this to be performed at Mayo Clinic (Rochester, MN).
- Able and willing to provide informed consent either signed by themselves or a legally authorized representative.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic in Rochester Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.