NCT07091162Completed
EValuation Of poLygenic Scores and CT imAging In Risk Factor Modification in Patients With diabEtes
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
This study is a three-arm, parallel-group, randomised controlled trial evaluating the effect of using cardiac CT imaging or polygenic risk score in cardiovascular risk factor modification in patients with diabetes.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 79 (actual)
- First submitted
- 18 Jun 2025
- Start date
- 25 Jul 2023
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Monash University
- Diseases
- Type 2 diabetes
- NCT number
- NCT07091162
What you commit to
- Study type: Interventional
- Participants enrolled: 79
- From 25 Jul 2023 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Clinically manifest CV disease
- Evidence of clinically significant coronary disease on CT that would preclude masking from participant's treating clinician for the duration of the study on the grounds of safety, including but not limited to, equal/greater than 50% in the left main coronary artery or equal/greater than 70% in any epicardial coronary artery
Other
- Unable to provide written informed consent.
- Unwilling to be followed for serial evaluation
- Unable to participate in the study or complete protocol required assessments in the opinion of the Investigator
Who the study is looking for
- Age 40 years or older
- Established diagnosis of T2DM
- Having acceptable imaging quality as deemed by the VHI-AICL
- Able to have a PRS calculated
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Victorian Heart Hospital Coordinator of this site? Confirm its status | Melbourne | Australia | Unknown status |
Related publications
- Patient Perspectives on a Nurse-Led Personalised Cardiovascular Risk Intervention in Type 2 Diabetes: A Qualitative Study Within the VOLTAIRE Trial.J Clin Nurs · 2026 · PMID 42850770
- Baseline Computed Tomography Coronary Angiography and Polygenic Risk Profiles in Adults With Type 2 Diabetes: A Cross-Sectional Analysis From the VOLTAIRE Study.Diabetes Obes Metab · 2026 · PMID 42420749
This page is information, not medical advice. Discuss any trial with your doctor.