NCT07092826Active, not recruiting
Obsessive-Compulsive Disorder: Insight, Trauma, and Links to Schizophrenia Spectrum Disorders
Obsessive-Compulsive Disorder: Formal and Content Modalities, Factors Involved in Loss of Insight, Role of Trauma, and Correlations With Schizophrenia Spectrum Disorders
Source: ClinicalTrials.gov · Last updated 11 Aug 2025
Brief summary (registry, in English)
This study aims to better understand Obsessive-Compulsive Disorder (OCD) by examining the types and patterns of OCD symptom presentation. The investigators seek to determine how these symptoms impact overall daily functioning. The study will also explore factors contributing to loss of insight in individuals with OCD, focusing on the potential roles of trauma, personality traits, and disorder severity. This may assist in identifying subgroups of patients who respond more favorably to treatment. Additionally, the study will investigate how individuals with OCD and schizophrenia spectrum symptoms respond to combined sensory stimuli (e.g., auditory and tactile). The goal is to determine whether these responses are associated with specific brain processing patterns, trauma history, or characteristics of compulsive behavior. Insights from this research may help clarify why certain individuals develop repetitive behaviors such as checking and rituals. Participants will be adults aged 18 to 65 diagnosed with OCD or schizophrenia spectrum disorders. Recruitment will occur through psychiatric clinics in Parma. Participation requires signed informed consent.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 3 Jun 2025
- Start date
- 1 Feb 2023
- Primary completion date
- 1 Feb 2026
- Lead sponsor
- Matteo Tonna
- Diseases
- Schizophrenia
- NCT number
- NCT07092826
What you commit to
- Study type: Observational
- Planned participants: 300
- From 1 Feb 2023 to the primary completion date, 1 Feb 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- General medical condition that may be related to the psychiatric disorder.
- Cognitive impairment (score below 25 on the Mini Mental State Examination).
Other
- Alcohol or substance dependence or abuse.
Who the study is looking for
- Diagnosis of Obsessive-Compulsive Disorder (OCD) and/or Schizophrenia Spectrum Disorder according to DSM-5 criteria (APA, 2013), as determined by a structured clinical interview (SCID-5-CV) (First et al., 2016).
- Age between 18 and 65 years.
- Participant agreement to take part in the study (informed consent).
Age in the registry: 18 years to 65 years · Sex: All
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Università degli Studi di Parma - Dipartimento di Medicina e Chirurgia Coordinator of this site? Confirm its status | Parma | Italy | Unknown status |
| University of Parma Coordinator of this site? Confirm its status | Parma | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.