NCT07092995Enrolling by invitation
Understanding Freezing of Gait Using Brain Signals and Virtual Reality
Leveraging Invasive Recordings and Immersive Virtual Reality to Characterize Freezing of Gait Mechanisms in Parkinson Disease
Source: ClinicalTrials.gov · Last updated 17 Feb 2026
Brief summary (registry, in English)
Freezing of gait - the inability to start or continue walking - is a particularly disabling problem in Parkinson's disease that has few treatment options. This project records human brain activity from deep brain stimulation (DBS) devices during walking and freezing of gait episodes to understand the pathophysiology of freezing of gait. Findings will lay the foundation for the development of new treatment strategies that address this disabling symptom.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 36 (estimated)
- First submitted
- 16 Jul 2025
- Start date
- 1 Nov 2025
- Primary completion date
- 31 Mar 2030
- Lead sponsor
- University of California, Los Angeles
- Diseases
- Parkinson disease
- NCT number
- NCT07092995
What you commit to
- Study type: Interventional
- Planned participants: 36
- From 1 Nov 2025 to the primary completion date, 31 Mar 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Clinical diagnosis of dementia or severe cognitive impairment (MOCA \< 21)
- History of stroke, traumatic brain injury, or other neurologic disorders besides Parkinson's disease
- Unstable medical condition including cardio-vascular instability in the past 6 months
Other
- Comorbidities causing severe gait impairments
- Unable or unwilling to comply with the testing protocol
Who the study is looking for
- Patients meeting the MDS clinical diagnostic criteria for Parkinson's disease who are implanted with a Medtronic Percept DBS Device and SenSight Directional Leads in bilateral globus pallidus internus (GPi).
- Able to walk unassisted indoors
- Age 18 or older
- Half of patients will have disabling freezing of gait as defined by freezing more than once per day by self-report on questions 1 \& 2 of the New Freezing of Gait Questionnaire
- The other half of patients will not have freezing of gait as defined by self-report on question 1 of the New Freezing of Gait Questionnaire
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California, Los Angeles Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.