NCT07094048RecruitingPhase 4
Immunoglobulins in Multiple Myeloma Patients Receiving a BCMA-Directed T Cell Engager
Source: ClinicalTrials.gov · Last updated 22 Jul 2026
Brief summary (registry, in English)
Bispecific antibody therapies targeting BCMA (B-cell maturation antigen) represent a novel therapeutic approach for patients with multiple myeloma. They are currently used in cases of refractory multiple myeloma but are also being investigated in earlier lines of treatment. However, these new therapies can lead to deeper immunosuppression and exacerbate an underlying immunosuppressive state in patients with multiple myeloma. As a result, infectious complications are common with these therapies and are a significant concern. Therefore, preventing infections in this population is crucial. However, data on the best strategies for prevention are currently lacking.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- First submitted
- 11 Jul 2025
- Start date
- 5 Jan 2026
- Primary completion date
- Dec 2028
- Lead sponsor
- CHU de Quebec-Universite Laval
- Diseases
- Multiple myeloma
- NCT number
- NCT07094048
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 80
- From 5 Jan 2026 to the primary completion date, Dec 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Less than 18 years old
Other
- Pregancy or breastfeeding
Who the study is looking for
- Multiple myeloma patient:
- ≥ 18 years old
- ≥ 1 prior lines of therapy
- Receiving a BCMA-directed T-cell Engager therapy (starting on treatment)
- On previous Ig support or not
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Santé Québec Chaudière-Appalaches Coordinator of this site? Confirm its status | Lévis | Canada | Recruiting |
| Centre Intégré de Cancérologie Coordinator of this site? Confirm its status | Québec | Canada | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.