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NCT07094048RecruitingPhase 4

Immunoglobulins in Multiple Myeloma Patients Receiving a BCMA-Directed T Cell Engager

Source: ClinicalTrials.gov · Last updated 22 Jul 2026

Brief summary (registry, in English)

Bispecific antibody therapies targeting BCMA (B-cell maturation antigen) represent a novel therapeutic approach for patients with multiple myeloma. They are currently used in cases of refractory multiple myeloma but are also being investigated in earlier lines of treatment. However, these new therapies can lead to deeper immunosuppression and exacerbate an underlying immunosuppressive state in patients with multiple myeloma. As a result, infectious complications are common with these therapies and are a significant concern. Therefore, preventing infections in this population is crucial. However, data on the best strategies for prevention are currently lacking.

Status (registry)
Recruiting
Phase (registry)
Phase 4
Study type
Interventional
Enrollment
80 (estimated)
First submitted
11 Jul 2025
Start date
5 Jan 2026
Primary completion date
Dec 2028
Lead sponsor
CHU de Quebec-Universite Laval
NCT number
NCT07094048

What you commit to

  • Study type: Interventional · Phase 4
  • Planned participants: 80
  • From 5 Jan 2026 to the primary completion date, Dec 2028
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Age

  • Less than 18 years old

Other

  • Pregancy or breastfeeding

Who the study is looking for

  • Multiple myeloma patient:
  • ≥ 18 years old
  • ≥ 1 prior lines of therapy
  • Receiving a BCMA-directed T-cell Engager therapy (starting on treatment)
  • On previous Ig support or not

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Santé Québec Chaudière-Appalaches
Coordinator of this site? Confirm its status
LévisCanadaRecruiting
Centre Intégré de Cancérologie
Coordinator of this site? Confirm its status
QuébecCanadaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.