NCT07095400Not yet recruiting
Evaluation of Functional and Biochemical Effectiveness of a Strength Training Protocol in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 31 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Parkinson's Disease (PD) is a complex neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons, which results in a range of motor symptoms such as tremor, rigidity, and bradykinesia, as well as non-motor symptoms including anxiety, depression, and cognitive decline. Strength training has emerged as a promising intervention to improve motor function and influence biochemical markers associated with oxidative stress and neurodegeneration. This study aims to evaluate the effectiveness of a structured strength training protocol over 12 weeks in improving both functional and biochemical outcomes in patients with PD.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 22 (estimated)
- First submitted
- 21 Jul 2025
- Start date
- 7 Sept 2025
- Primary completion date
- 1 Jun 2027
- Lead sponsor
- Universidad Villanueva
- Diseases
- Parkinson disease
- NCT number
- NCT07095400
What you commit to
- Study type: Interventional
- Planned participants: 22
- From 7 Sept 2025 to the primary completion date, 1 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Diagnosis of a condition other than PD.
- Significant comorbidities and/or severe systemic diseases that would prevent participation in exercise (e.g., recent surgery, cardiac instability, anemia, hepatosis, pulmonary disorders, chronic renal failure, or severe mental disorders).
Other
- Inability to actively understand instructions and cooperate in the tasks given, based on a score \<24 on the Mini-Mental State Examination (MMSE).
- Refusal to participate in the study.
- Stages I, IV, or V of the Hoehn and Yahr Scale.
Who the study is looking for
- Patients diagnosed with PD who meet the modified diagnostic criteria of the UK Brain Bank.
- Patients in stage II or III of the Hoehn and Yahr Scale.
- A score greater than 60% on the Schwab and England Functional Scale.
- Patients whose motor response to pharmacological treatment is stable or slightly fluctuating and who are not receiving any specific strength training rehabilitation treatment at the time of the study.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universidad Villanueva Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.