NCT07096726Not yet recruiting
Boston Medical Center Ultrasound Decongestion Study in Heart Failure
Boston Medical Center Ultrasound Decongestion Study
Source: ClinicalTrials.gov · Last updated 29 Sept 2026
Brief summary (registry, in English)
The purpose of this study is to analyze the utility of a novel five-point ultrasound as a predictor of volume overload in diverse patients who are admitted with volume overload/congestive heart failure (CHF) exacerbation at Boston Medical Center (BMC), the largest safety-net hospital in New England. Current standard of care (SOC) involves the utilization of laboratory markers and physical exam, which is often inconsistent and equivocal. The investigators will assess will assess if ultrasound-assisted diuresis reduces recurrent episodes of volume overload/decompensated heart failure.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- First submitted
- 24 Jul 2025
- Start date
- Nov 2026
- Primary completion date
- Dec 2027
- Lead sponsor
- Boston Medical Center
- Diseases
- Heart failure
- NCT number
- NCT07096726
What you commit to
- Study type: Interventional
- Planned participants: 200
- From Nov 2026 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Abdominal surgery in the past 1 month
- Severe acute kidney injury (AKI) or requiring renal replacement therapy
Other illness
- Significant acute or chronic liver disease
- End stage renal disease on dialysis
- Acute valvular disease
- Acute type 1 myocardial infarction
- Medical condition precluding abdominal ultrasound due to significant discomfort or pain
Lab values
- Advanced chronic kidney disease (CKD) \[Stage V CKD with glomerular filtration rate (GFR) \<15\] to exclude renal vein doppler ultrasound
Other
- Hemodynamic instability defined as systolic blood pressure \<85 mmHg or mean arterial pressure \<60 mm Hg for greater than 24 hours duration
- Known abdominal thrombus in the inferior vena cava (IVC) or portal vein
- Acute myocarditis
- Adults not able to provide consent (a simple teach back method of key aspects discussed in consent form will be utilized to verify if patient is able to adequately provide informed consent)
Who the study is looking for
- Patient with a primary diagnosis of acute on chronic decompensated heart failure who is admitted to inpatient or presents to the outpatient Boston Medical Center (BMC) Heart Failure Infusion clinic for decongestion treatment.
- Willing and able to receive short abdominal and thoracic ultrasounds throughout hospitalization
- Patients with right and/or left ventricular failure
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Boston Medical Center Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.