NCT07097870Not yet recruiting
Predictors of HCC in Post-HCV Cirrhotic Patients After SVR
Study of Clinical and Laboratory Predictors of Hepatocellular Carcinoma in Post-HCV Cirrhotic Patients After Sustained Virologic Response.
Source: ClinicalTrials.gov · Last updated 5 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study aims to identify clinical and laboratory factors that predict the occurrence of hepatocellular carcinoma (HCC) in Egyptian cirrhotic patients after achieving a sustained virologic response (SVR) to hepatitis C virus (HCV) treatment. This is a retrospective, two-center, case-control study that will include 132 cases and 264 controls. Variables to be analyzed include demographics, liver disease status, metabolic comorbidities, lifestyle factors, medications, as well as laboratory parameters and non-invasive scoring systems.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 400 (estimated)
- First submitted
- 24 Jul 2025
- Start date
- Aug 2025
- Primary completion date
- Sept 2025
- Lead sponsor
- Sohag University
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT07097870
What you commit to
- Study type: Observational
- Planned participants: 400
- From Aug 2025 to the primary completion date, Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- for cases:
- non HCV cirrhosis or combined HCV-HBV cirrhosis;
- HCC \<6 months before SVR;
- concomitant cholangiocarcinoma
Other
- for controls: Same as cases, plus, loss to follow up before 36 months
Who the study is looking for
- for cases:
- age ≥ 18 y;
- HCV related cirrhosis;
- SVR12 after DAA;
- radiologic or histologic HCC diagnosis ≤30 Jun 2025
- for controls: As above plus, ≥36 months post SVR without HCC
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of Medicine, Sohag Univesity Coordinator of this site? Confirm its status | Sohag | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.