NCT07098923Completed
The Effect of Exercise on Blood Pressure Variability on Peritoneal Dialysis Patients
The Effect of Combined Aerobic and Resistance Exercise on Blood Pressure Variability on Peritoneal Dialysis Patients
Source: ClinicalTrials.gov · Last updated 1 Aug 2025
Brief summary (registry, in English)
In China, the chronic kidney disease (CKD) incidence rate is as high as 10.8%. Renal replacement therapy plays an critical role in the later stage of CKD and becomes mandatory, as end-stage renal disease (ESRD) is unavoidable in progressive CKD. Peritoneal dialysis (PD) has becoming an essential alternative treatment for patient with end-stage renal disease (ESRD). Hypertension is common among ESRD patients receiving PD treatment, with a prevalence rate of 80% -90%, It is major cause for cardiovascular related complications and deaths among ESRD patients. Therefore hypertension increases the cardiovascular disease risk among the patients of ESRD and at the same time plays an independent risk for the progression of ESRD. Most studies uses average blood pressure as a risk indicator, but in recent years, more evidence has shown that blood pressure variability (BPV), the degree of fluctuation of blood pressure for a long period, is an additional risk factors for cardiovascular events.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 55 (actual)
- First submitted
- 23 Jul 2025
- Start date
- Feb 2024
- Primary completion date
- Jul 2024
- Lead sponsor
- The Affiliated Hospital of Xuzhou Medical University
- Diseases
- Chronic kidney disease
- NCT number
- NCT07098923
What you commit to
- Study type: Interventional
- Participants enrolled: 55
- From Feb 2024 to the primary completion date, Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- There have been recent acute cardiovascular and cerebrovascular events, including vascular embolism, surgery, trauma, etc.
Other illness
- Cardiac function Class IV - In accordance with The New York Heart Association classification system, patients with severe cardiac disease resulting in inability to perform any physical activity without discomfort (If any physical activity is undertaken, discomfort is increased) or symptoms of cardiac insufficiency or of the anginal syndrome may be present even at rest.
Other
- Blood pressure more than - systolic blood pressure ≥ 180mmHg, diastolic blood pressure ≥ 110mmHg;
- Severe anaemia Hb ≤ 60g;
- Using erythropoietin;
Who the study is looking for
- Dialysis time ≥ 3 months, a stable condition;
- Age ≥ 18 years old;
- Hypertension (blood pressure\>140 and/or 90 mmHg or currently under antihypertensive drugs), antihypertensive drugs was not changed or replaced during the complete trial;
- Patients with regular and sufficient peritoneal dialysis with kt/v\>1.7, high compliance, and voluntary participation.
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The affiliated hospital of xuzhou medical university Coordinator of this site? Confirm its status | Xuzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.