NCT07099027Recruiting
The Lung Health Check Pilot
Source: ClinicalTrials.gov · Last updated 1 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study aims to test if it is feasible to introduce lung cancer screening in Ireland. People within a certain age group, who smoke or who smoked in the past, are at a greater risk of developing lung cancer. They can also develop chronic lung conditions that can affect their long-term health. In Ireland, about 2,690 people are diagnosed with Lung Cancer every year. Unfortunately, 2 out of every 3 people diagnosed with lung cancer die per year. The goal of this study is to try to screen for lung cancer in people before they have symptoms associated with the disease. We aim to do this by selecting people based on their age, whether they have smoked in the past or currently smoke as well as other relevant factors. People who take part in this study will have an assessment of how their lungs work and a low-dose CT scan. This is called a lung health check. The goal of the low-dose CT scan is to pick up lung cancer before it becomes symptomatic, and at an earlier stage. This scan uses a very low dose of radiation. Unfortunately, without early detection, such as is the goal of this trial, 8 out of 10 people who go on to develop lung cancer will have advanced lung cancer when it is discovered, where outcomes tend to be poor. The earlier detection of lung cancer has a greater potential for treatment. Current international recommendations suggest carrying out these scans in the community rather than in a hospital. Therefore, we aim to deliver these lung health checks using a mobile unit in the community. This study aims to test if we will successfully pick up lung cancer earlier by doing community-based 'lung health check's using mobile units in North Dublin and the North East, among people of a certain age and smoking history.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 2183 (estimated)
- First submitted
- 6 May 2025
- Start date
- 19 May 2025
- Primary completion date
- 15 Feb 2026
- Lead sponsor
- Royal College of Surgeons, Ireland
- Diseases
- Lung cancer
- NCT number
- NCT07099027
What you commit to
- Study type: Interventional
- Planned participants: 2183
- From 19 May 2025 to the primary completion date, 15 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Participant-reported history of chest CT in the last 12 months
- Participant reported known diagnosis of other advanced stage cancers
- Participant reported diagnosis of lung cancer of any stage in the last 5 years
Other
- Inability to undergo non-contrast CT (e.g. \>200 kg body weight, inability to lie flat)
- Likely non-compliance with study procedures, as determined by the participant i) Unable to provide informed consent ii) Inability to attend study visits
- Nursing home residents -
Who the study is looking for
- 55 - 74 years of age
- Current or former smokers
- Current: \>100 cigarettes in lifetime and/or currently tobacco smoking
- Former: \>100 cigarettes in lifetime and/or no tobacco smoking \>= 28 days
- Referred from a GP for the LHC pilot
- PLCOM2012 ≥ 1.51% or LLPv2 ≥2.5% (Lung Cancer Risk Scores)
- Prostate Lung Cancer Colorectal Ovarian (PLCO) \& Liverpool Lung Project Version 2 (LLPv2)
Age in the registry: 55 years to 74 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Beaumont RCSI Cancer Centre Coordinator of this site? Confirm its status | Dublin | Ireland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.