NCT07099677Recruiting
Short-Term Effects of Antihypertensive Drugs on Postural Balance and Fall Risk
The Effect of Antihypertensive Medication Use on Fall Risk: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 12 Feb 2026
Brief summary (registry, in English)
The goal of this clinical trial is to compare the short-term effects of three commonly prescribed antihypertensive drug classes (beta-blockers, ACE inhibitors, and calcium channel blockers) on postural balance and fall risk in adults with newly diagnosed primary hypertension. The main questions it aims to answer are: * Do different antihypertensive drugs affect objective balance performance and fall risk? * What are the effects of these medications on dizziness and fear of falling? Researchers will use a balance analysis system (Biodex Balance System) and self-reported scales (Dizziness Handicap Inventory and Falls Efficacy Scale) to assess outcomes. Participants will: * Be randomly assigned to one of three drug groups (metoprolol, ramipril, or amlodipine) * Be evaluated at baseline (prior to treatment), at 2 weeks, and at 4 weeks after starting treatment * Complete balance tests and questionnaires at each time point This study aims to provide clinical insight into how commonly used blood pressure medications may impact balance and fall risk in real-world settings.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 186 (estimated)
- First submitted
- 25 Jul 2025
- Start date
- 1 Aug 2025
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Abant Izzet Baysal University
- Diseases
- High blood pressure
- NCT number
- NCT07099677
What you commit to
- Study type: Interventional
- Planned participants: 186
- From 1 Aug 2025 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of medications that may affect balance (e.g., sedatives, psychotropic drugs)
Other illness
- Secondary hypertension
- Known diagnosis of vestibular disorders (e.g., BPPV, Ménière's disease)
- History of falls due to trauma unrelated to balance
- Cognitive impairment preventing proper test participation
Other
- Inability to complete the assessments at follow-up timepoints (2nd and 4th week)
Who the study is looking for
- Aged between 18 and 75 years
- Newly diagnosed with primary hypertension
- No prior use of antihypertensive medication
- No history of neurological, vestibular, orthopedic, or psychiatric conditions affecting balance
- Able to walk independently without assistive devices
- Provided written informed consent to participate in the study
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bolu Abant Izzet Baysal University, Izzet Baysal Training and Research Hospital Coordinator of this site? Confirm its status | Bolu | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.