NCT07100483Enrolling by invitation
Comparing Surgical Management Methods of Atrial Fibrillation
Prospective, Randomized Trial Comparing Left Atrial Cox-Maze IV, Tampa 2 or Encompass Alone, Ablation in the Surgical Management of Atrial Fibrillation
Source: ClinicalTrials.gov · Last updated 16 Jul 2026
Brief summary (registry, in English)
Compare the efficacy of the left atrial Cox-Maze IV lesion set versus the Tampa 2 lesion set versus the EnCompass ablation alone, in the surgical treatment of atrial fibrillation at one year post-operatively.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 220 (estimated)
- First submitted
- 11 Jul 2025
- Start date
- Sept 2025
- Primary completion date
- Sept 2027
- Lead sponsor
- Corewell Health West
- Diseases
- Atrial fibrillation
- NCT number
- NCT07100483
What you commit to
- Study type: Interventional
- Planned participants: 220
- From Sept 2025 to the primary completion date, Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of VT/VF, WPW
- Re-operative cardiac surgery
Lab values
- LVEF \< 25%
Other
- LAVI \> 59ml/m②
- Presence of Pacemaker/AICD
Who the study is looking for
- Adult patients with a history of preoperative atrial fibrillation, either paroxysmal or persistent, requiring concomitant surgical ablation who are scheduled to undergo cardiac surgical procedure(s) to be performed on cardiopulmonary bypass
- Utilizing sternotomy approach requiring cardiopulmonary bypass
- Male or Female subjects between age 18 to 85 years of age
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Corewell Health West Coordinator of this site? Confirm its status | Grand Rapids | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.