NCT07103122Active, not recruiting

Virtual Reality Therapy for Arm Recovery (VVITA) Stroke

Personalized Adaptive Mirror Therapy for Upper-Limb Post-Stroke Rehabilitation Using Virtual Reality and Myoelectric Control: VVITAstroke Pilot RCT

Source: ClinicalTrials.gov · Last updated 5 Aug 2025

Brief summary (registry, in English)

The study exploits new technologies appeared in the consumer electronics market to provide stroke patients with a low-cost, easy-to-use upper limb rehabilitation tool based on virtual reality. It aims to assess the potential, validity and participation in therapy while using virtual reality to improve limb rehabilitation through rehabilitation exercises that will use games chosen to improve the capabilities of the paretic upper limb. This therapy will be administered in addition to normal therapy and will be compared with a control group that will carry out the regular conventional therapy plus a neuromotor therapy dedicated to the upper limb of equal time and dose of interventional therapy.

Status (registry): Active, not recruiting
Study type: Interventional
Enrollment: 24 (actual)
First submitted: 11 Jul 2025
Start date: Mar 2022
Primary completion date: Jun 2027
Lead sponsor: I.R.C.C.S. Fondazione Santa Lucia
Diseases: Stroke
NCT number: NCT07103122

What you commit to

Study type: Interventional
Participants enrolled: 24
From Mar 2022 to the primary completion date, Jun 2027
1 site in 1 country
Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Criteria the registry did not label

Individuals affected by stroke with upper limb deficits with sufficient level of muscle power, so that movement is possible with gravity eliminated (F=2), or muscle movement is possible against gravity (F=3), as assessed with Medical Research Council (MRC) scale grades not below 1
havinge reported at least 18 but not more than 54 out of 66, respectively 27% and 80% of the upper limb functionality, as assessed with the Upper Limb Extremity section of the Fugl-Meyer Assessment (FMA) scale
not having e reportedabsence of severe linguistic impairments which may limit the understanding of the instructions;
not having e reportedabsence of cognitive impairments, assessed with the Addenbrooke's Cognitive Examination - Revised version for Italian population, visual deficit or other neurologic disease in comorbidity, which may affect the patient's ability to interact with the VR environment.

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

Site	City	Country	Site status
IRCCS Fondazione Santa Lucia Coordinator of this site? Confirm its status	Roma	Italy	Unknown status

Related publications

Usability, Acceptability, and Feasibility of a Personalized Adaptive Mirror Therapy for Upper-Limb Poststroke Rehabilitation Using Immersive Virtual Reality and Myoelectric Control: Single-Arm Pre-Post Study.JMIR Rehabil Assist Technol · 2026 · PMID 42082173

This page is information, not medical advice. Discuss any trial with your doctor.