Effect of Acute Exercise on Biochemical Parameters in Normal-Weight and Overweight/Obese Adolescent.

Brief summary (registry, in English)

The goal of this interventional clinical trial is to compare the acute physiological and biochemical responses to maximal physical exercise (Spartacus test). in two groups of adolescent girls: in normal-weight and overweight/obese adolescent. The main question it aims to answer: * Does Spartacus test significantly alter glucose metabolism and lipid profile in normal-weight and overweight/obese adolescent? * How do inflammatory markers such as C-Reactive Protein \[CRP\], Erythrocyte Sedimentation Rate \[ESR\], respond immediately after and 30 minutes following maximal effort? * Are there significant changes in liver enzymes (Aspartate Aminotransferase \[AST\], Alanine Aminotransferase \[ALT\]), muscle damage indicators (creatine kinase \[CK\], Lactate Dehydrogenase \[LDH\]), and electrolyte balance post-exercise? Participants will undergo a baseline blood draw before performing the Spartacus test , a progressive maximal exercise test. Blood samples will then be collected immediately after the test and again 30 minutes post-exercise to evaluate changes in: Glucose metabolism (fasting glucose), Lipid profile (total cholesterol, High-Density Lipoprotein \[HDL\], Low-Density Lipoprotein \[LDL\], triglycerides), Liver and muscle enzymes (Aspartate Aminotransferase \[AST\], Alanine Aminotransferase \[ALT\], Creatine kinase \[CK\], Lactate Dehydrogenase \[LDH\]), Renal function markers (creatinine, urea), Inflammatory markers (C-Reactive Protein \[CRP\], Erythrocyte Sedimentation Rate \[ESR\]), Hematological profile (complete blood count: White Blood Cells \[WBC\], Red Blood Cells \[RBC\], Hemoglobin \[Hb\], Hematocrit \[Hct\], platelets), Electrolytes (sodium, potassium, chloride), Uric acid, calcium, phosphorus, magnesium, iron.

What you commit to

• Study type: Interventional
• Participants enrolled: 35
• From 10 Aug 2025 to the primary completion date, 13 Aug 2025
• 1 site in 1 country
• Visits and tests: ask the trial team, the registry does not list them

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Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Who the study is looking for

Age in the registry: 13 years to 18 years · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

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