NCT07104539Recruiting
Strength Training Response of Muscle in GLP-1 Users
Source: ClinicalTrials.gov · Last updated 21 Jan 2026
Brief summary (registry, in English)
GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function. Moreover, any loss of muscle mass or muscle function with GLP-1 treatment may impair balance and increase fall risk. This is a particular concern among older adults already susceptible to the common muscle strength and muscle function loss with age, yet there is little evidence among this population. This study will address a gap in knowledge regarding the effects of GLP-1 treatment on muscle mass, muscle function, and balance/fall risk among adults age 50 and older.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 29 Jul 2025
- Start date
- 8 Oct 2025
- Primary completion date
- Dec 2026
- Lead sponsor
- Virginia Polytechnic Institute and State University
- Diseases
- Obesity
- NCT number
- NCT07104539
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 8 Oct 2025 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Active metabolic, neoplastic, or cardiovascular disease
Age
- Age \<50
Other
- Weight \>300 lb
- Osteoporosis
- Unable or unwilling to provide consent
Who the study is looking for
- Age, 50y+
- Be taking GLP-1 medicine (Weygovy or Zepbound) for 1 month or less
- Weight \<300 lb
- Pass a health and exercise readiness screening
Age in the registry: 50 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Virginia Tech Coordinator of this site? Confirm its status | Blacksburg | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.