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NCT07104539Recruiting

Strength Training Response of Muscle in GLP-1 Users

Source: ClinicalTrials.gov · Last updated 21 Jan 2026

Brief summary (registry, in English)

GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function. Moreover, any loss of muscle mass or muscle function with GLP-1 treatment may impair balance and increase fall risk. This is a particular concern among older adults already susceptible to the common muscle strength and muscle function loss with age, yet there is little evidence among this population. This study will address a gap in knowledge regarding the effects of GLP-1 treatment on muscle mass, muscle function, and balance/fall risk among adults age 50 and older.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
30 (estimated)
First submitted
29 Jul 2025
Start date
8 Oct 2025
Primary completion date
Dec 2026
Lead sponsor
Virginia Polytechnic Institute and State University
Diseases
Obesity
NCT number
NCT07104539

What you commit to

  • Study type: Interventional
  • Planned participants: 30
  • From 8 Oct 2025 to the primary completion date, Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Active metabolic, neoplastic, or cardiovascular disease

Age

  • Age \<50

Other

  • Weight \>300 lb
  • Osteoporosis
  • Unable or unwilling to provide consent

Who the study is looking for

  • Age, 50y+
  • Be taking GLP-1 medicine (Weygovy or Zepbound) for 1 month or less
  • Weight \<300 lb
  • Pass a health and exercise readiness screening

Age in the registry: 50 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Virginia Tech
Coordinator of this site? Confirm its status
BlacksburgUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.