NCT07104682Active, not recruitingEarly phase 1
A Study to Determine the Safety and Effectiveness of the Investigational Cellular Therapy GCAR1 in a Patient With Alveolar Soft Part Sarcoma
An Open Label Individual Patient Study Investigating the Safety and Efficacy of GCAR1 in a Patient With Metastatic Relapsed Alveolar Soft Part Sarcoma
Source: ClinicalTrials.gov · Last updated 4 Aug 2026
Brief summary (registry, in English)
A single patient study to determine whether GCAR1 is safe and effective for refractory, progressive metastatic alveolar soft part sarcoma (ASPS).
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Early phase 1
- Study type
- Interventional
- Enrollment
- 1 (estimated)
- First submitted
- 29 Jul 2025
- Start date
- 21 Aug 2025
- Primary completion date
- 19 Jan 2027
- Lead sponsor
- University of Calgary
- Diseases
- Childhood cancers, Sarcoma
- NCT number
- NCT07104682
What you commit to
- Study type: Interventional · Early phase 1
- Planned participants: 1
- From 21 Aug 2025 to the primary completion date, 19 Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any anti-cancer therapy within 21 calendar days prior to the first dose of lymphodepleting chemotherapy
Other illness
- Any active uncontrolled infection
Who the study is looking for
- The patient must have relapsed ASPS that is in the opinion of the treating physician not resectable, or that resection would be associated with significant morbidity.
- The patient must provide informed consent.
- The only other eligibility criteria is adequate organ function, defined as creatinine clearance \>30 ml/min and LVEF \>45%.
Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Of Calgary Coordinator of this site? Confirm its status | Calgary | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.